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Invitrogen™ ZNF496 Polyclonal Antibody
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Catalog No. PIPA540311
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100 μL
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PIPA540311 100 μL
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Catalog No. PIPA540311 Supplier Invitrogen™ Supplier No. PA540311
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Description

Rabbit Polyclonal Antibody

Peptide sequence: QEKPHECSVC GELFSDSEDL DGHLESHEAQ KPYRCGACGK SFRLNSHLLS Sequence homology: Cow: 86%; Dog: 93%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%; Sheep: 86%.

ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF496
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene ZNF496
Gene Accession No. Q96IT1
Gene Alias MGC15548; NIZP1; Nizp11; NSD1 (nuclear receptor binding SET-domain containing 1)-interacting zinc finger protein 1; NSD1-interacting zinc finger protein 1; Zfp496; zinc finger protein 496; Zinc finger protein with KRAB and SCAN domains 17; zinc finger with KRAB and SCAN domains 17; Zkscan17; ZNF496; ZSCAN49
Gene Symbols ZNF496
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human ZNF496.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84838
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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