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ZNF496 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982409
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100 μL
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50-198-2409 100 μL
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Catalog No. 50-198-2409 Supplier Bioss Supplier No. BS12815R
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Rabbit Polyclonal Antibody

ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.

Specifications

Antigen ZNF496
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ZNF496
Gene Accession No. Q96IT1
Gene Alias BOS_7947; MGC15548; Nizp1; Nizp11; NSD1 (nuclear receptor binding SET-domain containing 1)-interacting zinc finger protein 1; NSD1-interacting zinc finger protein 1; Zfp496; Zinc finger protein 496; Zinc finger protein with KRAB and SCAN domains 17; zinc finger with KRAB and SCAN domains 17; Zkscan17; Znf496; ZSCAN49
Gene Symbols ZNF496
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ZNF496.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84838
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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