Invitrogen™ ZNF50 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106774

Catalog No. PIPA5106774

Description

Antibody detects endogenous levels of total ZSCAN22.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZSCAN22 (zinc finger and SCAN domain-containing protein 22), also known as HKR2 or ZNF50 (zinc finger protein 50), is a 491 amino acid nuclear protein. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZSCAN22 contains eight C2 H2-type zinc fingers and one SCAN box domain. ZSCAN22 may be involved in transcriptional regulation, and becomes phosphorylated upon DNA damage.

Specifications

• Antigen: ZNF50
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZSCAN22
• Gene Alias: AW227621; D530006B18Rik; GLI-Kruppel family member HKR2; HKR2; Krueppel-related zinc finger protein 2; LOC102553002; Protein HKR2; zinc finger and SCAN domain containing 22; zinc finger and SCAN domain-containing protein 22; Zinc finger protein 50; zinc finger protein 8-like; ZNF50; ZSCAN22
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 102553002, 232878, 342945
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P10073
• Gene Symbols: ZSCAN22
• Immunogen: A synthesized peptide derived from human ZSCAN22(Accession P10073), corresponding to amino acid residues A321-Q371.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG