Invitrogen™ ZNF503 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555439

Catalog No. PIPA555439

Description

Immunogen sequence: SPSSKLSSVA SNGGGAGGAG GGAAGDKDTK SGPLKLSDIG VEDKSSFKPY SKPGSDKKEP GGGGGGGGGG GGGGGGVSSE KSGFRVPSAT CQPFTPRTGS PSSSASACSP GGMLSSAGGA PEGKDDKKDT DVG Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

The ZNF503 gene encodes zinc finger protein 503, a transcription factor involved in the regulation of developmental processes and cellular differentiation. ZNF503 contains zinc finger domains that enable it to bind DNA and modulate the transcription of specific target genes, influencing pathways critical for embryonic development, particularly in the neural and mesenchymal tissues. It plays a substantial role in the regulation of stem cell differentiation and has been implicated in various biological processes, including neuronal migration, immune response, and organogenesis. Alterations in ZNF503 expression have been linked to developmental anomalies and diseases such as cancers, where it affects tumor growth and progression by modulating gene networks involved in cell proliferation and differentiation. Research into ZNF503 focuses on understanding its complex regulatory functions and potential as a target for therapeutic interventions in developmental disorders and oncological applications.

Specifications

• Antigen: ZNF503
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZNF503
• Gene Alias: Nlz2; NOLZ1; NOLZ-1; Zinc finger protein 503; ZNF503
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84858
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96F45
• Gene Symbols: ZNF503
• Immunogen: Recombinant protein corresponding to Human ZNF503. Recombinant protein control fragment (Product #RP-102302).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG