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Invitrogen™ ZNF521 Polyclonal Antibody
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Catalog No. PIPA534388
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100 μg
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Catalog No. Quantity
PIPA534388 100 μg
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Catalog No. PIPA534388 Supplier Invitrogen™ Supplier No. PA534388
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Description

Rabbit Polyclonal Antibody

A suggested positive control is Hela cell lysate. PA5-34388 can be used with blocking peptide PEP-1431.

The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
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Specifications

Antigen ZNF521
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ZNF521
Gene Accession No. Q96K83
Gene Alias B930086A16Rik; early hematopoietic zinc finger protein; Ecotropic viral integration site 3 protein; EHZF; Evi3; LIP3; LYST-interacting protein 3; Zfp521; Zinc finger protein 521; Znf521
Gene Symbols ZNF521
Host Species Rabbit
Immunogen An 18 amino acid synthetic peptide near the amino terminus of human ZNF521.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25925
Target Species Human
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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