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Invitrogen™ ZNF521 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534388

Catalog No. PIPA534388


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Description

Description

A suggested positive control is Hela cell lysate. PA5-34388 can be used with blocking peptide PEP-1431.

The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ZNF521
Polyclonal
Unconjugated
ZNF521
B930086A16Rik; early hematopoietic zinc finger protein; Ecotropic viral integration site 3 protein; EHZF; Evi3; LIP3; LYST-interacting protein 3; Zfp521; Zinc finger protein 521; Znf521
Rabbit
Antigen affinity chromatography
RUO
25925
Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 0.02% sodium azide
Q96K83
ZNF521
An 18 amino acid synthetic peptide near the amino terminus of human ZNF521.
100 μg
Primary
Human
Antibody
IgG
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