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ZNF521 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987637
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100 μL
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50-198-7637 100 μL
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Catalog No. 50-198-7637 Supplier Bioss Supplier No. BS6978R
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Description

Rabbit Polyclonal Antibody

The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.

Specifications

Antigen ZNF521
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ZNF521
Gene Accession No. Q96K83
Gene Alias B930086A16Rik; Early hematopoietic zinc finger protein; Ecotropic viral integration site 3 protein; EHZF; Evi3; LIP3; LYST-interacting protein 3; Zfp521; Zinc finger protein 521; Znf521
Gene Symbols ZNF521
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human EHZF/ZNF521.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25925
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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