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Invitrogen™ ZNF598 Monoclonal Antibody (1E2)
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Catalog No. PIMA522840
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100 μg
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Catalog No. Quantity
PIMA522840 100 μg
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Catalog No. PIMA522840 Supplier Invitrogen™ Supplier No. MA522840
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Description

Mouse Monoclonal Antibody

Peptide Sequence: SCVLCCGDLE ATALGRCDHP VCYRCSTKMR VLCEQRYCAV CREELRQVVF GKKLPAFATI PIHQLQHEKK YDIYFADGKV YALYRQLLQH ECPRCPELP.

ZNF598 (E3 ubiquitin-protein ligase ZNF598) plays a key role in the ribosome quality control (RQC). RQC is a pathway that takes place when a ribosome has stalled during translation. It is required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40A ribosomal protein RPS10/eS10 and RPS3/uS3. Stalling precludes synthesis of a long poly-lysine tail and initiated the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF598
Applications ELISA, Immunocytochemistry
Classification Monoclonal
Clone 1E2
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene ZNF598
Gene Accession No. Q86UK7
Gene Alias BC023040; C6orf149; E3 ubiquitin-protein ligase ZNF598; FLJ00086; ISD11; Ntrap; Zfp598; Zinc finger protein 598; ZNF598
Gene Symbols ZNF598
Host Species Mouse
Immunogen ZNF598 (NP_835461, 28 a.a. ~ 126 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 90850
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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