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Invitrogen™ ZNF598 Polyclonal Antibody
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Catalog No. PIPA531409
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100 μL
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PIPA531409 100 μL
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Catalog No. PIPA531409 Supplier Invitrogen™ Supplier No. PA531409
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Zebrafish (85%), Xenopus laevis (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ZNF598 (E3 ubiquitin-protein ligase ZNF598) plays a key role in the ribosome quality control (RQC). RQC is a pathway that takes place when a ribosome has stalled during translation. It is required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40A ribosomal protein RPS10/eS10 and RPS3/uS3. Stalling precludes synthesis of a long poly-lysine tail and initiated the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF598
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene ZNF598
Gene Accession No. Q80YR4, Q86UK7
Gene Alias BC023040; C6orf149; E3 ubiquitin-protein ligase ZNF598; FLJ00086; ISD11; Ntrap; Zfp598; Zinc finger protein 598; ZNF598
Gene Symbols Zfp598, ZNF598
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ZNF598. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 213753, 90850
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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