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Invitrogen™ ZNF83 Polyclonal Antibody
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Catalog No. PIPA555281
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100 μL
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PIPA555281 100 μL
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Catalog No. PIPA555281 Supplier Invitrogen™ Supplier No. PA555281
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HGRKDDAQKQ PVKNQLGLNP QSHLPELQLF QAEGKIYKYD HMEKSVNSSS LVSPPQRISS TVKTHISHTY ECNFVDSLFT QKEKANIGTE HYKCSERGKA FHQGLHFTIH QIIHTKETQF KCDICGKIFN KKSNLASHQR IHTGEKPYKC Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 37%.

The ZNF83 gene encodes a zinc-finger protein belonging to a large family of transcription factors that play essential roles in regulating gene expression by interacting with DNA. Located on chromosome 3, ZNF83 is particularly notable for its recurrent mutations in cancer. For instance, the p.E293V missense mutation in ZNF83 has been frequently observed in bladder cancer patients, accounting for 18% of cases, and is associated with poor prognosis. This mutation disrupts the gene's tumor suppressor function, promoting increased tumor growth. Due to its significant role in tumorigenesis, ZNF83 is actively studied in cancer research as a potential biomarker and therapeutic target.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF83
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ZNF83
Gene Accession No. P51522
Gene Alias HPF1; zinc finger protein 816B; Zinc finger protein 83; zinc finger protein HPF1; ZNF816B; ZNF83
Gene Symbols ZNF83
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZNF83. Recombinant protein control fragment (Product #RP-89397).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55769
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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