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Invitrogen™ ZNHIT2 Polyclonal Antibody
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Catalog No. PIPA563517
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100 μL
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PIPA563517 100 μL
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Catalog No. PIPA563517 Supplier Invitrogen™ Supplier No. PA563517
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CTPVVPTRIP AIVSLSRGPV SPLVRFQLPN VLFAYAHTLA LYHGGDDALL SDFCATLLGV SGALGAQQVF ASAEEAL Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.

The ZNHIT2 gene, located on chromosome 7, encodes a zinc-finger HIT-type containing protein crucial for various cellular processes, such as chromatin remodeling and gene transcription regulation. Knockout studies in mice reveal that ZNHIT2, alongside ZNHIT1, is essential during early development, with deficits leading to embryonic lethality during peri-implantation stages due to reduced proportions of pluripotent inner cell mass cells and aberrant expression of key developmental genes like NANOG and SOX17. This gene's relevance extends to its involvement in protein-protein and protein-nucleic acid interactions that are fundamental in cellular functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNHIT2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Znhit2
Gene Accession No. Q9UHR6
Gene Alias C11orf5; FON; ORF6; Protein FON; RGD1307918; zinc finger HIT domain-containing protein 2; zinc finger HIT-type containing 2; zinc finger, HIT domain containing 2; zinc finger, HIT domain containing 2, pseudogene; zinc finger, HIT type 2; zinc finger, HIT-type containing 2; Znhit2; Znhit2-ps
Gene Symbols Znhit2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZNHIT2. Recombinant protein control fragment (Product #RP-99907).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 741
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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