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Invitrogen™ ZNRF1 Polyclonal Antibody
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Catalog No. PIPA537982
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100 μg
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Catalog No. Quantity
PIPA537982 100 μg
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Catalog No. PIPA537982 Supplier Invitrogen™ Supplier No. PA537982
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with human, rat, dog, pig and cow based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. Regulates Schwann cells differentiation by mediating ubiquitination of GLUL. Promotes neurodegeneration by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons (Probable).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNRF1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene ZNRF1
Gene Accession No. Q8ND25, Q91V17
Gene Alias B830022L21Rik; E3 ubiquitin-protein ligase ZNRF1; MGC101991; nerve injury gene 283; nerve injury-induced gene 283 protein; Nin283; peripheral nerve injury protein nin283; ring finger protein 42; RING-type E3 ubiquitin transferase ZNRF1; Rnf42; zgc:77896; zinc and ring finger 1; zinc and ring finger 1, E3 ubiquitin protein ligase; zinc and ring finger protein 1; zinc ring finger protein 1; zinc/RING finger protein 1; ZNRF1; Zrfp1
Gene Symbols ZNRF1
Host Species Goat
Immunogen Peptide with sequence C-SDSTYAHGNGYQET, from the internal region of mouse Znrf1 (aa 93-107).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170737, 84937
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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