Invitrogen™ ZP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552577

Catalog No. PIPA552577

Description

Immunogen sequence: FAVNLNQEAT SPPVLIAWDN QGLLHELQND SDCGTWIRKG PGSSVVLEAT YSSCYVTEWD SHYIMPVGVE GAGAAEHKVV TERKLLKCPM DLLARDAPDT DWCDSIPA Highest antigen sequence identity to the following orthologs: Mouse - 23%, Rat - 54%.

The mammalian zona pellucida is composed of four major glycoproteins, ZP1, ZP2, ZP3 and ZP4, which may act as sperm receptors. Two forms of porcine ZP4 peptides exist: one consisting of 128 amino acid residues and the other of 133 amino acid residues. These two peptides are identical, except the larger form contains an additional five amino acid sequence at its carboxy-terminal end. Both peptides have two potential N-linked glycosylation sites. The smaller peptide shares 39.1% identity with the amino-terminal region of mouse ZP2 polypeptide. Based on results from animal studies, ZP4 antigen is a promising candidate for the development of a contraceptive vaccine.

Specifications

• Antigen: ZP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZP4
• Gene Alias: Processed zona pellucida sperm-binding protein 4; ZBP; zona pellucida 4; zona pellucida B glycoprotein; zona pellucida glycoprotein 4; Zona pellucida protein B; zona pellucida sperm-binding protein 4; ZP1; ZP4; Zp-4; ZPB
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57829
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q12836
• Gene Symbols: ZP4
• Immunogen: Recombinant protein corresponding to Human ZP4. Recombinant protein control fragment (Product #RP-90149).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov