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Invitrogen™ ZPK Polyclonal Antibody
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Catalog No. PIPA5100731
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PIPA5100731 100 μL
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Catalog No. PIPA5100731 Supplier Invitrogen™ Supplier No. PA5100731
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MAP3K12.

ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZPK
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MAP3K12
Gene Accession No. Q12852, Q60700, Q63796
Gene Alias DLK; Dual leucine zipper bearing kinase; dual leucine zipper kinase; dual leucine zipper kinase DLK; leucine zipper protein kinase; leucine-zipper protein kinase; M3KC; MAP3K12; MAPK-upstream kinase; MEKK12; Mitogen activated protein kinase 12 (Zipper (leucine) protein kinase); mitogen activated protein kinase kinase kinase 12; mitogen-activated protein kinase kinase kinase 12; Mixed lineage kinase; MUK; PK; protein kinase MUK; zipper (leucine) protein kinase; Zpk; ZPKP1
Gene Symbols MAP3K12
Host Species Rabbit
Immunogen A synthesized peptide derived from human MAP3K12(Accession Q12852), corresponding to amino acid residues R8-P58.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25579, 26404, 7786
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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