Invitrogen™ ZPK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100731

Catalog No. PIPA5100731

Description

Antibody detects endogenous levels of total MAP3K12.

ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.

Specifications

• Antigen: ZPK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAP3K12
• Gene Alias: DLK; Dual leucine zipper bearing kinase; dual leucine zipper kinase; dual leucine zipper kinase DLK; leucine zipper protein kinase; leucine-zipper protein kinase; M3KC; MAP3K12; MAPK-upstream kinase; MEKK12; Mitogen activated protein kinase 12 (Zipper (leucine) protein kinase); mitogen activated protein kinase kinase kinase 12; mitogen-activated protein kinase kinase kinase 12; Mixed lineage kinase; MUK; PK; protein kinase MUK; zipper (leucine) protein kinase; Zpk; ZPKP1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25579, 26404, 7786
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q12852, Q60700, Q63796
• Gene Symbols: MAP3K12
• Immunogen: A synthesized peptide derived from human MAP3K12(Accession Q12852), corresponding to amino acid residues R8-P58.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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