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ZRANB2 Mouse anti-Human, Clone: OTI2E3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF809526

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family. Localized to the nucleus, ZNF265 functions as a splicing factor that is responsible for alternatively splicing Tra-2 beta (transformer-2 beta) transcripts and is thought to interfere with constitutive 5′-splice selection. ZNF265 contains two RanBP2-type zinc fingers through which it conveys its RNA-binding activity. Two isoforms, designated ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.Specifications
ZRANB2 | |
Monoclonal | |
Unconjugated | |
ZRANB2 | |
ZIS, ZIS1, ZIS2, ZNF265 | |
Mouse | |
Affinity Chromatography | |
RUO | |
9406 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin) | |
OTI2E3 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
O95218 | |
ZRANB2 | |
Human recombit protein fragment corresponding to amino acids 95-320 of human ZRANB2 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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