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ZRANB2 Mouse anti-Human, Clone: OTI2E3, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF809526

Encompass_Preferred

Catalog No. 50-166-9559


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family. Localized to the nucleus, ZNF265 functions as a splicing factor that is responsible for alternatively splicing Tra-2 beta (transformer-2 beta) transcripts and is thought to interfere with constitutive 5′-splice selection. ZNF265 contains two RanBP2-type zinc fingers through which it conveys its RNA-binding activity. Two isoforms, designated ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.
Specifications

Specifications

ZRANB2
Monoclonal
Unconjugated
ZRANB2
ZIS, ZIS1, ZIS2, ZNF265
Mouse
Affinity Chromatography
RUO
9406
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin)
OTI2E3
PBS with 8% trehalose and no preservative; pH 7.3
O95218
ZRANB2
Human recombit protein fragment corresponding to amino acids 95-320 of human ZRANB2 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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