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Invitrogen™ ZRANB2 Polyclonal Antibody
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Catalog No. PIPA584523
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100 μL
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PIPA584523 100 μL
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Catalog No. PIPA584523 Supplier Invitrogen™ Supplier No. PA584523
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DEDEDDADLS KYNLDASEEE DSNKKKSNRR SRS Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family. Localized to the nucleus, ZNF265 functions as a splicing factor that is responsible for alternatively splicing Tra-2 beta (transformer-2 beta) transcripts and is thought to interfere with constitutive 5'-splice selection. ZNF265 contains two RanBP2-type zinc fingers through which it conveys its RNA-binding activity. Two isoforms, designated ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZRANB2
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Zranb2
Gene Accession No. O95218
Gene Alias AI227013; DKFZp686J1831; DKFZp686N09117; wu:fa96h03; Zfp265; zgc:56597; zinc finger protein 265; Zinc finger Ran-binding domain-containing protein 2; Zinc finger Ran-binding domain-containing protein 2-like protein; zinc finger RANBP2-type containing 2; zinc finger, RAN-binding domain containing 2; zinc finger, splicing; zinc-finger protein 265; zinc-finger, splicing; ZIS; ZIS1; ZIS2; Znf265; ZRANB2
Gene Symbols Zranb2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZRANB2. Recombinant protein control fragment (Product #RP-107114).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9406
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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