Invitrogen™ ZSCAN4 Monoclonal Antibody (2-7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA534914

Catalog No. PIMA534914

Description

Positive Control: 293 tranfected Zscan4, 293T, HepG2, human liver tissue.

Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells. Loss-of-function studies using siRNA shows delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development. ZSCAN4 plays an important role in the preimplantation development. Also, ZSCAN4 is involved in telomere maintenance and long term genomic stability in ES cells, suggesting that ZSCAN4 may be of critical importance in maintaining pluripotency in replicating stem cells.

Specifications

• Antigen: ZSCAN4
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q8NAM6
• Gene Symbols: ZSCAN4
• Immunogen: Recombinant protein within Human ZSCAN4 aa 1-138.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Western Blot
• Clone: 2-7
• Conjugate: Unconjugated
• Gene: ZSCAN4
• Gene Alias: BQ559217; C330039H09Rik; RGD1563625; zinc finger and SCAN domain containing 4; zinc finger and SCAN domain containing 4A; zinc finger and SCAN domain containing 4F; zinc finger and SCAN domain containing protein 4F; Zinc finger and SCAN domain-containing protein 4; zinc finger protein 494; ZNF494; ZSCAN4; Zscan4a; Zscan4f
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 201516
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles, store in dark
• Form: Liquid