Invitrogen™ ZSCAN4 Monoclonal Antibody (2-7)

Catalog No.	Quantity
PIMA534914	100 μL

Catalog No. PIMA534914 Supplier Invitrogen™ Supplier No. MA534914

Description

Mouse Monoclonal Antibody

Positive Control: 293 tranfected Zscan4, 293T, HepG2, human liver tissue.

Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells. Loss-of-function studies using siRNA shows delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development. ZSCAN4 plays an important role in the preimplantation development. Also, ZSCAN4 is involved in telomere maintenance and long term genomic stability in ES cells, suggesting that ZSCAN4 may be of critical importance in maintaining pluripotency in replicating stem cells.

Specifications

• Antigen: ZSCAN4
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 2-7
• Concentration: 2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4
• Gene: ZSCAN4
• Gene Accession No.: Q8NAM6
• Gene Alias: BQ559217; C330039H09Rik; RGD1563625; zinc finger and SCAN domain containing 4; zinc finger and SCAN domain containing 4A; zinc finger and SCAN domain containing 4F; zinc finger and SCAN domain containing protein 4F; Zinc finger and SCAN domain-containing protein 4; zinc finger protein 494; ZNF494; ZSCAN4; Zscan4a; Zscan4f
• Gene Symbols: ZSCAN4
• Host Species: Mouse
• Immunogen: Recombinant protein within Human ZSCAN4 aa 1-138.
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 201516
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles, store in dark
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b