Invitrogen™ ZUFSP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560709

Catalog No. PIPA560709

Description

Immunogen sequence: RINTVQYGTS DNKKDNTLQC GMEVNSSILS GCASNHPKNS AQNLTKDSTL KHEGFYSENL TESRKFLKSR EKQSSLTEIK GSVYETTYSP PECPFCGKIE EHSEDMETHV KTKHANLLDI PLEDCDQPLY DCPMC Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 64%.

Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.

Specifications

• Antigen: ZUFSP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZUFSP
• Gene Alias: 2700019D07Rik; C6orf113; dJ412I7.3; DUB; Lys-63-specific deubiquitinase ZUFSP; zinc finger with UFM1 specific peptidase domain; zinc finger with UFM1-specific peptidase domain; zinc finger with UFM1-specific peptidase domain protein; Zinc finger-containing ubiquitin peptidase 1; Zufsp; Zup1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 221302
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96AP4
• Gene Symbols: ZUFSP
• Immunogen: Recombinant protein corresponding to Human ZUFSP. Recombinant protein control fragment (Product #RP-88721).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG