Invitrogen™ ZWINT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA592903

Catalog No. PIPA592903

Description

Immunogen sequence: MEAAETEAEA AALEVLAEVA GILEPVGLQE EAELPAKILV EFVVDSQKKD KLLCSQLQVA DFLQNILAQE DTAKGLDPLA SEDTSRQKAI AAKEQWKELK ATYREHVEAI KIGLTKALTQ MEEAQRKRTQ LREAFEQLQA KKQMAMEKRR AVQNQWQLQQ EKHLQHLAEV SAEVRERKTG TQQELDRVFQ KLGNLKQQAE QERDKLQRYQ TFLQLLYTLQ GKLLFPEAEA EAENLPDDKP QQPTRPQEQS TGDTMGRDPG VSFKAVGLQP AGDVNLP; Positive Samples: 293T, SW620, HepG2, Jurkat, Mouse brain; Cellular Location: Chromosome, Nucleus, centromere, kinetochore.

This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: ZWINT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZWINT
• Gene Alias: 2010007E07Rik; 2600001N01Rik; D10Ertd749e; human ZW10 interacting protein-1; HZwint-1; KNTC2AP; neuroprotective protein 8; scoilin; Sip30; SNAP25 interacting protein 30; SNAP25 interacting protein of 30 kDa; SNAP25-interacting protein 30; ZW10 interacting kinetochore protein; ZW10 interacting protein-1; ZW10 interactor; ZW10 interactor, kinetochore protein; ZW10-interacting protein 1; ZWINT; ZWINT1; Zwint-1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11130, 257644, 52696
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.01 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O95229, Q8VIL3, Q9CQU5
• Gene Symbols: ZWINT
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human ZWINT (NP_0089882).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG