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  5. Tocris Bioscience™ ZYS 1

Tocris Bioscience™ ZYS 1

Catalog No. 892150
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Catalog No. Quantity
89-215-0 50 mg
89-211-0 10 mg
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Catalog No. 89-215-0 Supplier Tocris Bioscience™ Supplier No. 8921/50
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Description

ADAR1 (adenosine deaminase acting on RNA 1) deaminase inhibitor

ZYS 1 is an ADAR1 (adenosine deaminase acting on RNA 1) deaminase inhibitor (IC50 = 946 nM). In vitro, ZYS 1 exhibits antiproliferative activity against multiple prostate cancer cell lines. In vivo, ZYS 1 displays antitumor efficacy in prostate cancer cell-derived xenograft mouse model (20 mg and 40 mg per kg (body weight) intraperitoneally, with tumor growth inhibition rates of 66.68% and 81.83%, respectively).

Specifications

Chemical Name or Material 5'-Chloro-5'-deoxy-2-fluoroadenosine
CAS 2734853-80-4
Quantity 50 mg
Target Deaminase Inhibitors
Molecular Formula C10H11ClFN5O3
Purity 98%
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