The Maybridge collection offers a comprehensive range of chemistry products and services tailored to the drug discovery and biotechnology sector. For over 50 years, Maybridge has been at the forefront of innovative heterocyclic building block and screening compound design. The company is fueled by the desire to access novel molecules of pharmaceutical interest.
New Pack Sizes & Price Reductions
Maybridge is adding 1,300 large pack sizes for products with ex-stock availability and offering price reductions on more than 5,000 selected products!
Our new offering takes away the need to choose between different libraries by providing the ultimate coverage of drug-like chemical space with a single library. Building on over 50 years of expertise in designing industry leading screening libraries the pre-plated HitCreator represents the diversity of a 500,000 compound library distilled to 14,000 molecules. Each Maybridge HitCreator is conveniently supplied as dry films in Thermo Scientific™ Matrix 96 shallow-well plates or 384-well microplates.
The core of the Maybridge building block collection, these pharmacophorically rich intermediates are specifically designed for medicinal chemistry, allowing logical SAR development and Hit-to-Lead optimization. Many will be of particular interest as "privileged structures" while others bearing solubilizing moieties add to the pharmacokinetic profile of drug molecules.
A highly diverse set of over 53,000 hit-like and lead-like molecules widely acknowledged as a critical tool in screening campaigns.
A recent publication by the Journal of Chemical Information and Modeling describes the use of Maybridge screening compounds in the identification of novel ligase inhibitors procuring some top ranking compounds for enzyme based and cell based in vitro screening against colon cancer.
A highly diverse set of more than 53,000 hit-like and lead-like molecules widely acknowledged as a critical tool in screening campaigns.
Chemical compounds originating from the Maybridge™ HitFinder™ Library were employed to block the action of Arginine Methyltransferase 1 (PRMT1, an enzyme involved in inflammatory condition). Learn more in a recent publication from the Journal of Medicinal Chemistry.
30,000 small compounds (mw<300) taken from the complete Maybridge collection for use in fragment screening to further accelerate the identification of lead compounds.
The Maybridge Ro3 Diversity Library is a diverse selection of 2500 products from the complete Fragment Collection. It is fully Ro3 compliant with assured quality of greater or equal to 95 percent purity and assured solubility.
14,400 compounds selected to represent the overall diversity of the screening collection available pre-plated at 1µmol in 96-well plates or .25µmol in 384-well plates.
The Maybridge HitFinder Library assisted in finding novel drugs to treat Schistosomiasis, a tropical disease associated with high rates of morbidity and mortality.
Find out more in a recent article from the Chinese Center for Disease Control and Prevention.
The entire Maybridge screening collection of over 53,000 compounds is available off-the-shelf, pre-plated as 1umol dry films in 96 well plate format. Exceptional diversity and outstanding value!
The ultimate diversity screening library. Our new offering takes away the need to choose between different libraries by providing the ultimate coverage of drug-like chemical space with a single library. Building on 50 years of expertise in designing industry leading screening libraries, the Maybridge Global HitFinder is derived from a rigorous analysis of more than 5 million commercially available screening compounds and represents the characteristics of all the different commercial libraries.
Maybridge Chiral Resolution Screening and Purification Kits using 384 different combinations of resolving agents and solvents, these ready-to-use kits can reduce time to identify the best separation conditions to just one day.