Biochemical Reagents
Selleck Chemical LLC Fluorometholone
Fluorometholone (Oxylone) is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye
eMolecules Medchem Express / Guggulsterone / 5mg / 482203886 / HY-107738 / / 95975-55-6 / MFCD01310757 / 312.453 / C21H28O2
Medchem Express / Guggulsterone / 5mg / 482203886 / HY-107738 / / 95975-55-6 / MFCD01310757 / 312.453 / C21H28O2
Medchemexpress LLC (Z)-Guggulsterone | 39025-23-5 | 99.4% | 312.45 | 10 MG
(Z)-Guggulsterone is a constituent found in the Indian Ayurvedic medicinal plant Commiphora mukul. It functions by inhibiting the growth of human prostate cancer cells through apoptosis and hinders angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling pathway. It also acts as a potent FXR antagonist, reducing ACE2 expression and inhibiting SARS-CoV-2 infection. This product is intended for research use only and is not sold to patients.
- Inhibits growth of human prostate cancer cells through apoptosis
- Hinders angiogenesis by suppressing VEGF-VEGF-R2-Akt signaling
- Acts as a potent FXR antagonist
- Reduces ACE2 expression
- Inhibits SARS-CoV-2 infection
Medchemexpress LLC Z-guggulsterone | 39025-23-5 | MFCD01310757 | 99.4% | 312.45 g/mol | C21H28O2 | 5 MG
(Z)-Guggulsterone is a plant-derived sterol (CAS 39025-23-5) isolated from Commiphora mukul. It acts as a farnesoid X receptor (FXR) antagonist with reported activities including induction of apoptosis, inhibition of angiogenesis, and modulation of ACE2 expression, and is used in biochemical and cell-signaling research.
- Potent farnesoid X receptor (FXR) antagonist.
- Induces apoptosis in multiple cancer cell lines.
- Inhibits angiogenesis via the VEGF-VEGFR2-Akt pathway.
- Reported to reduce ACE2 expression and SARS-CoV-2 infection in studies.
- Suitable for biochemical and signaling pathway research applications.
Medchemexpress LLC (Z)-Guggulsterone | 39025-23-5 | 99.4% | 312.45 | 100 MG
(Z)-Guggulsterone, a constituent of the Indian Ayurvedic medicinal plant *Commiphora mukul*, has been shown to inhibit the growth of human prostate cancer cells by inducing apoptosis. It also inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling pathway. Additionally, (Z)-Guggulsterone acts as a potent FXR antagonist and has been observed to reduce ACE2 expression and SARS-CoV-2 infection.
- Inhibits growth of human prostate cancer cells by inducing apoptosis.
- Inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling pathway.
- Acts as a potent FXR antagonist.
- Reduces ACE2 expression and SARS-CoV-2 infection.
- Decreases level of VEGF-R2 protein in HUVEC.
- Reduces ACE2 and SHP levels in primary airway and intestinal organoids.
Sigma Aldrich Fine Chemicals Biosciences Escin United States Pharmacopeia (USP) Reference Standard | 11072-93-8 | 350MG
Escin United States Pharmacopeia (USP) Reference Standard | 11072-93-8 | 350MG
Medchemexpress LLC Estrone (Standard) | 53-16-7 | 99.7% | 25 MG
Estrone (Standard) is the analytical standard of Estrone and is intended for research and analytical applications. Estrone (E1) is a natural estrogenic hormone, representing a main endogenous estrogen produced by various tissues, particularly adipose tissue. It is formed through the aromatization of androstenedione in fat cells.
- Used as an analytical standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
- Appearance: Solid
- Color: White to off-white
- Initial source: Microorganisms, endogenous metabolite
- Store under recommended conditions in the Certificate of Analysis
Sigma Aldrich Fine Chemicals Biosciences Estrone >=99% | 53-16-7 | MFCD00003620 | 5G
Estrone >=99% | Purity: >=99% | Mol Wt: 270.37 | 53-16-7 | MFCD00003620 | 5G
Medchemexpress LLC Estrone sulfate potassium | 1240-04-6 | 99.9% | 388.52 | 50 MG
Estrone sulfate potassium is an inactive endogenous estrogen, convertible to Estrone and Estradiol, and a substrate of the OATP1B3 transporter. It stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, making it applicable to breast cancer-related research.
- Inactive endogenous estrogen
- Can be converted into Estrone and Estradiol
- Substrate of the OATP1B3 transporter
- Stimulates growth of mammary tumors in ovariectomized rats
- Promotes colony formation of dispersed mammary cells
- Useful for breast cancer-related research
Medchemexpress LLC Estrone sulfate (potassium) | 1240-04-6 | 99.9% | 388.52 | 1 ML
Estrone sulfate potassium is an inactive endogenous estrogen that can be converted into Estrone and Estradiol. It is also a substrate of the OATP1B3 transporter. This compound is applicable to breast cancer-related research, as it stimulates the growth of nitrosomethylurea-induced mammary tumors and promotes colony formation of dispersed nitrosomethylurea mammary cells through its conversion to Estrone and Estradiol.
- Taken up at a low rate by normal breast parenchymal cells.
- Converted to estrone by normal breast parenchymal cells.
- Stimulates colony formation in dispersed nitrosomethylurea mammary cells.
- Exerts dose-related stimulatory effects on nitrosomethylurea-induced hormone-responsive mammary tumor growth in castrate rats.
- Reduces glucose-6-phosphatase activity and protein levels, and lowers blood glucose in ob/ob mice.
- Modulates glucose-6-phosphatase kinetic parameters in control mice.
Chem-Impex International, Inc. Dehydroepiandrosterone | MFCD00003613 | 25G
Dehydroepiandrosterone, MFCD00003613, 25G
Medchemexpress LLC Estrone O-sulfamate | 148672-09-7 | 100.0% | C18H23NO4S | 10MG
Estrone O-sulfamate is a research-grade steroid sulfatase inhibitor supplied as a high-purity solid for biochemical and pharmacological studies. It is intended for use in assays of steroid metabolism and enzyme inhibition, with recommended refrigerated storage and solvent stability guidelines for long-term experiments.
- Potent steroid sulfatase (STS) inhibitor suitable for in vitro studies.
- High purity solid for reliable analytical and biological assays.
- White to off-white powder, convenient for weighing and formulation.
- Stable under recommended storage conditions and protected from light.
- Available in small research pack sizes to minimize waste and enable pilot studies.