Isotope Standards
Boron 11 Isotope Standard For ICP/MS, 10μg/mL in H20, SPEX CertiPrep™
CAS: 7440-42-8 Molecular Formula: B Molecular Weight (g/mol): 10.81 MDL Number: MFCD00134034 MFCD00151272 InChI Key: ZOXJGFHDIHLPTG-UHFFFAOYSA-N PubChem CID: 5462311 ChEBI: CHEBI:27560 IUPAC Name: boron SMILES: [B]
Lithium 6 Isotope Standard For ICP/MS, SPEX CertiPrep™
CAS: 7439-93-2 Molecular Formula: Li Molecular Weight (g/mol): 6.94 MDL Number: MFCD00134051 InChI Key: WHXSMMKQMYFTQS-UHFFFAOYSA-N PubChem CID: 3028194 ChEBI: CHEBI:30145 IUPAC Name: lithium SMILES: [Li]
Lead 206 Isotope Standard For ICP/MS, SPEX CertiPrep™
CAS: 7439-92-1 Molecular Formula: Pb Molecular Weight (g/mol): 207.20 MDL Number: MFCD00134050 InChI Key: WABPQHHGFIMREM-UHFFFAOYSA-N PubChem CID: 5352425 ChEBI: CHEBI:27889 IUPAC Name: lead SMILES: [Pb]
Medchemexpress LLC Linezolid-d8 | 1032182-14-1 | 345.40 | 1 MG
PNU-100766-d8 is a deuterated and labeled form of Linezolid (HY-10394). Linezolid (PNU-100766) belongs to the oxazolidinone class of synthetic antibiotics. Its mechanism of action involves inhibiting the initiation of bacterial protein synthesis. It is utilized in the treatment of severe infections caused by Gram-positive bacteria that have developed resistance to other antibiotics.
- Targets antibiotic, bacterial, and isotope-labeled compounds
- Involved in anti-infection and other pathways
- Incorporation of stable heavy isotopes of elements like hydrogen, carbon, and others into drug molecules serves primarily as tracers for quantitative analysis during drug development
- Deuteration is noted for its potential to influence the pharmacokinetic and metabolic characteristics of drugs
- Inhibits bacterial protein synthesis through its binding to rRNA on both the 30S and 50S ribosomal subunits
Medchemexpress LLC Phenothiazine-d8 | 1219803-41-4 | MFCD08705020 | 99.0% | 207.32 | C12HD8NS | 5mg
Phenothiazine-d8 is the deuterium labeled Phenothiazine Phenothiazine is an antibiotic which has insecticidal fungicidal antibacterial and anthelmintic activities Phenothiazine also can be used for the research of neurological diseases[1][2]
Medchemexpress LLC (S)-praziquantel-d11 | 00-00-0 | 98.2% | 323.47 g/mol | C19H13D11N2O2 | 5 MG
(S)-Praziquantel-d11 is the deuterium-labeled S-enantiomer of praziquantel supplied as a research standard and analytical reference. It is intended for laboratory use as an internal standard or tracer in mass spectrometry and other analytical workflows; not for human or clinical use.
- Deuterium-labeled S-enantiomer for use as an internal standard.
- High purity: 98.2%.
- Chemical formula: C19H13D11N2O2.
- Molecular weight: 323.47 g/mol.
- Supplied as a small-quantity powder suitable for analytical applications.
- For research use only; not for human or clinical use.
Cayman Chemical CholIc ACDd4 MaxSpec Stnd
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
Medchemexpress LLC PF-06380101-d8 (Aur0101-d8) | 1436391-86-4 | 99.27% | 751.06 | 1 MG
PF-06380101-d8 (Aur0101-d8) is a deuterium labeled PF-06380101. It functions as an Auristatin microtubule inhibitor and is a cytotoxic Dolastatin 10 analogue. This compound is valuable for various applications in research and drug development, leveraging its stable isotope properties.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, primarily as tracers for quantitation during drug development.
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 21-Deoxycortisol-d8 | 2479914-04-8 | 98.79% | 354.51 | 1 MG
21-Deoxycortisol-d8 is the deuterium labeled 21-Deoxycortisol. 21-Deoxycortisol is an endogenous metabolite and a sign of congenital adrenal hyperplasia. This compound can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC ABT-737-d8 | 1217686-68-4 | 99.1% | C42H37D8ClN6O5S2 | 100 UG
ABT-737-d8 is the deuterium labeled ABT-737, a BH3 mimetic and a potent inhibitor of Bcl-2, Bcl-xL, and Bcl-w. It induces the disruption of the BCL-2/BAX complex and BAK-dependent, BIM-independent activation of the intrinsic apoptotic pathway, and also induces autophagy.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Has potential for acute myeloid leukemia (AML) research
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
- For research use only
Medchemexpress LLC Enalaprilat-d5 | 349554-00-3 | 99.5% | 10 MG
Enalaprilat-d5 is a deuterium-labeled analogue of enalaprilat used as a reference standard in biochemical and pharmacokinetic research. It acts as an angiotensin-converting enzyme (ACE) inhibitor and is provided as a high-purity analytical standard for assay development and quantitation.
- Deuterium-labeled internal standard for analytical assays.
- High isotopic enrichment and 99.5% purity for reliable quantitation.
- Suitable for LC-MS/MS method development and validation.
- Available in small pack sizes (for example, 10 mg) for bench-scale work.
- Supplied as a dry powder for convenient dissolution and storage.
Medchemexpress LLC L-Phenylalanine-d8 | 17942-32-4 | 99.6% | 173.24 | 1 MG
L-Phenylalanine-d8 is a deuterium labeled L-Phenylalanine. As an essential amino acid isolated from Escherichia coli, L-Phenylalanine acts as an α2δ subunit of voltage-dependent Ca+ channels antagonist. It is also a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) and non-NMDARs. Stable heavy isotopes, such as deuterium in this compound, are incorporated into molecules for use as tracers in drug development, with potential benefits for pharmacokinetic and metabolic profiles.
- Acts as an α2δ subunit antagonist of voltage-dependent Ca+ channels
- Functions as a competitive antagonist for glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs)
- Used as a tracer in various applications
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Applied in the production of food flavors and pharmaceuticals
Medchemexpress LLC (S)-2-(2-Amino-2-methylpropanamido)-N-((3R,4S,5S)-3-methoxy-1-((S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)-N-methyl-3-(methyl-d3)butanamide-2,3,4,4,4-d5 | 1436391-86-4 | 99.3% | 751.06...
PF-06380101-d8 is a deuterium-labeled PF-06380101, which is an Auristatin microtubule inhibitor and a cytotoxic Dolastatin 10 analogue. This compound can be used as a tracer and an internal standard for quantitative analysis in various applications.
- Deuterium labeled compound.
- Auristatin microtubule inhibitor.
- Cytotoxic dolastatin 10 analogue.
- Stable heavy isotopes are incorporated for use as tracers for quantitation during drug development.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.