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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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ABT-418 hydrochloride is a potent, selective nicotinic acetylcholine receptor (nAChR) agonist supplied as the hydrochloride salt for preclinical research. It exhibits cognitive-enhancing and anxiolytic activities and is used in pharmacology and receptor studies.
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Medchemexpress,HY-B0470 10g Neomycin (sulfate) CAS:1405-10-3 Formula:C23H52N6O25S3 Neomycin sulfate is an aminoglycoside antibiotic and calcium channel inhibitor. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Paromomycin sulfate (Aminosidine sulfate) is a broad-spectrum aminoglycoside antibiotic and a derivative of neomycin. It functions by prematurely terminating mRNA translation and inhibiting protein synthesis through specific binding to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. This compound demonstrates both amebicidal and bactericidal properties, making it valuable for research into bacterial and parasitic infections.
Broad-spectrum aminoglycoside antibiotic activity
Exhibits amebicidal and bactericidal properties
Inhibits protein synthesis by targeting bacterial 30S ribosomes
Useful for research on bacterial and parasitic infections
Reduces intracellular parasitic forms in Caco-2 and HCT-8 cells in vitro
Reduces C. parvum oocysts in infected mice in vivo
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ABT-418 hydrochloride is the hydrochloride salt of a selective neuronal nicotinic acetylcholine receptor (nAChR) agonist used for preclinical research. It is supplied as a light brown to brown solid, with characterized purity and solubility suitable for formulation and biological testing.
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Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
Peg-based PROTAC linker
Click chemistry reagent
Contains an Azide group for CuAAc and SPAAC reactions
For research use only
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Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
Utilized in the synthesis of PROTACs
Functions as a click chemistry reagent
Contains an azide group
Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules
Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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U-Blot Pan-O-GlcNAc Rabbit mAb (Recombinant Monoclonal Clone W-R7) is a Rabbit-derived recombinant monoclonal antibody (clone W-R7) that specifically recognizes O-GlcNAc a o-glcnacylation modification at Ser(S)/Thr(T) It shows reactivity with Human Mouse Rat Validated applications include WB IHC IF ELISA Recommended dilutions WB 1200-11000 IF 1200-11000 ELISA 15000-120000 Purified by recombinant antibody expressed in animal component-free (acf) media purified via protein a affinity chromatography O-GlcNAc (short for O-linked -N-acetylglucosamine) is a reversible enzymatic post-translational modification found on serine and threonine residues of nucleocytoplasmic proteins The modification is characterized by a -glycosidic bond between the hydroxyl group of serine or threonine side chains and N-acetylglucosamine (GlcNAc) Supplied as 100 uL
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U-Blot Pan-O-GlcNAc Rabbit mAb (Monoclonal) is a Rabbit-derived monoclonal antibody that specifically recognizes O-GlcNAc a o-glcnacylation modification at Ser(S)/Thr(T) O-GlcNAc (short for O-linked -N-acetylglucosamine) is a reversible enzymatic post-translational modification found on serine and threonine residues of nucleocytoplasmic proteins The modification is characterized by a -glycosidic bond between the hydroxyl group of serine or threonine side chains and N-acetylglucosamine (GlcNAc) It is widely involved in the regulation of diverse cellular processes including transcription cell cycle signal transduction and stress response Dysregulation of O-GlcNAcylation has been closely linked to cancer neurodegeneration diabetes and inflammatory diseases Notably elevated O-GlcNAc levels in many cancers have been reported to suppress apoptosis by inhibiting caspase activation Supplied as 100 uL
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