Carbohydrates
Chem-Impex International, Inc. 5-Bromo-4-chloro-3-indolyl-b-D-galactopyranoside | 7240-90-6 | MFCD00005666 | 1G
5-Bromo-4-chloro-3-indolyl-b-D-galactopyranoside, 7240-90-6, MFCD00005666, 1G
AdipoGen n-Octyl-beta-D-glucopyranoside
Chemical. CAS 29836-26-8. Formula C14H28O6. MW 292.4. Non-ionic detergent for the functional solubilization, isolation, purification and crystallograpy of membrane proteins. Mild, non-denaturing detergent that is used for the solubilization and reconstitution of membrane-bound proteins in their native state and for the preparation of lipid vesicles. Its well-defined chemical structure, small uniform micelles and high water solubility make it superior to most other non-ionic detergents for membrane solubilization. The high critical micelle concentration 0.7% of n-octylglucoside facilitates ready removal from final protein extracts by dialysis or gel filtration. Used in lysis and solubilisation buffers for bacterial lipoprotein preparations, mitochondrial extracts or for determination of protein content by BCA assay. Can be used in 2D electrophoresis.
Medchemexpress LLC D-(+)-Trehalose dihydrate | 6138-23-4 | 378.33 | 25 MG
D-(+)-Trehalose dihydrate (Standard) is the analytical standard of D-(+)-Trehalose dihydrate, isolated from Saccharyomyces cerevisiae. It serves as a reference standard for research and analytical applications, and can also be used as a food ingredient and pharmaceutical excipient.
- Intended for research and analytical applications.
- Isolated from Saccharomyces cerevisiae.
- Can be used as a food ingredient.
- Can be used as a pharmaceutical excipient.
- Utilized in qualitative, quantitative, and methodological research experiments.
- Suitable for techniques such as HPLC, GC, and MS.
Medchemexpress LLC D-Thyroxine | 51-49-0 | 98.02% | C15H11I4NO4 | 5 MG
D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. It can inhibit goiter, promote metamorphosis of tadpoles, and influence cholesterol metabolism. It is used for the study of hypercholesterolemia.
- Orally active thyroid hormone
- Inhibits TSH secretion
- Can inhibit goiter
- Promotes metamorphosis of tadpoles
- Influences cholesterol metabolism
- Used for the study of hypercholesterolemia
- Molecular weight: 776.87
- Chemical formula: C15H11I4NO4
- CAS number: 51-49-0
- Solid form
- Light yellow to light brown color
Medchemexpress LLC ODN D-SL01 sodium | DNA, d(P-thio)(T-C-G-C-G-A-C-G-T-T-C-G-C-C-C-G-A-C-G-T-T-C-G-G-T-A), sodium salt | 1 MG
ODN D-SL01 sodium is a class B CpG oligodeoxynucleotide and a TLR9 agonist. It exhibits strong immunostimulatory activity in various vertebrate species and possesses anticancer activity.
- Class B CpG oligodeoxynucleotide
- TLR9 agonist
- Strong immunostimulatory activity in various vertebrate species
- Possesses anticancer activity
- Oligonucleotide for cancer immunotherapy research
Medchemexpress LLC Tetrahydrouridine dihydrate | 18771-50-1 | MFCD00063468 | C9H20N2O8 | 5 MG
Tetrahydrouridine dihydrate (THU dihydrate) is a potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine. It is intended for research use only.
- Potent inhibitor of cytidine deaminase (CDA)
- Competitively blocks CDA's active site
- More effective than intrinsic cytidine
- Can sensitize some pancreatic and lung carcinoma cells to gemcitabine-induced cell death
- Inhibits s-phase without apoptosis
Medchemexpress LLC D-64131 | 74588-78-6 | C16H13NO2 | 1 ML
D-64131 is an orally active tubulin inhibitor that demonstrates antimitotic activity by binding to β-tubulin, destabilizing microtubules, and arresting mitotic cells in the M-phase. This compound effectively inhibits the proliferation of tumor cells from various organs and tissues, making it a subject of cancer research.
- Orally active compound
- Inhibits tubulin polymerization
- Exhibits antimitotic effects
- Shows antiproliferative activity against tumor cells
- Effective against multidrug-resistant tumor cell lines
Medchemexpress LLC d-KLA Peptide | 286380-05-0 | 99.3% | 1523.99 | 1 MG
d-KLA Peptide is a synthetic pro-apoptotic peptide that specifically targets mitochondria and induces apoptosis by destroying the mitochondrial membrane. It activates biochemical pathways associated with apoptosis, including the activation of caspase family proteins and PARP (poly ADP ribose polymerase). d-KLA Peptide can be used to carry and deliver genes or small molecules to enhance anti-tumor effects.
- Specific targeting of mitochondria to induce apoptosis
- Destroys the mitochondrial membrane
- Activates caspase family proteins and PARP
- Can enhance anti-tumor effects when used to carry and deliver genes or small molecules
Medchemexpress LLC D-Psicose-d (D-Allulose-d) | 53685-24-8 | 99.9% | 181.16 | 5 MG
D-Psicose-d is the deuterium labeled D-Psicose. D-psicose is an orally active rare sugar that inhibits p38-MAPK phosphorylation and MCP-1 expression. It also inhibits the AGEs/RAGE/NF-κB pathway. D-psicose protects pancreatic β-islets, improving hyperglycemia and high-fat diet-induced non-alcoholic fatty liver disease.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
- Deuteration affects the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Sapintoxin D | 80998-07-8 | 99.9% | 1 MG
Sapintoxin D is a fluorescent phorbol ester used for studying the activation of protein kinase C (PKC). It acts as a calcium-dependent PKC activator and exhibits antiviral activity against HIV2 ROD, HIV1 3B in MT4 cells, and chikungunya virus in Vero cells. Its molecular weight is 539.62, and its formula is C30H37NO8. It appears as a white to off-white solid and is derived from Plants Euphorbiaceae Shirakiopsis indica (Willd.) Esser. It is intended for research use only.
- Fluorescent phorbol ester
- Utilized for studying the activation of protein kinase C (PKC)
- Calcium-dependent PKC activator
- Demonstrated antiviral activity against HIV2 ROD and HIV1 3B in MT4 cells
- Demonstrated antiviral activity against chikungunya virus in Vero cells
- White to off-white solid appearance
- Derived from Plants Euphorbiaceae Shirakiopsis indica
- For research use only
Medchemexpress LLC D-3263 hydrochloride | 1008763-54-9 | 98.12% | 409.95 | 100 MG
D-3263 hydrochloride is an enteric-coated, orally bioavailable transient receptor potential melastatin member 8 (TRPM8) agonist. It binds to and activates TRPM8, which may lead to an increase in calcium and sodium entry, disruption of calcium and sodium homeostasis, and induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may also decrease dihydrotestosterone (DHT) levels, potentially contributing to its inhibitory effects on prostate cancer and benign prostatic hyperplasia (BPH).
- Binds to and activates TRPM8.
- Increases calcium and sodium entry into cells.
- Disrupts calcium and sodium homeostasis.
- Induces cell death in TRPM8-expressing tumor cells.
- Decreases dihydrotestosterone (DHT) levels.
- Inhibits prostate cancer and benign prostatic hyperplasia (BPH).
Medchemexpress LLC Ophiopogonin D | 945619-74-9 | 855.02 | 10 MM * 1 ML
Ophiopogonin D is a naturally occurring C29 steroidal glycoside isolated from *Ophiopogon japonicus*. It acts as a CYP2J3 inducer and shows protective effects against inflammatory, metabolic, and cardiovascular diseases.
- Inhibits Ang II induced NF-κB nuclear translocation.
- Increases expression of CYP2J2/EETs and PPARα in HUVECs.
- Inhibits osteoclastic differentiation in RAW264.7 cells.
- Protects against H2O2-induced endothelial injury as an antioxidant.
- Blocks ERK signaling cascades.
- Alleviates high-fat diet-induced metabolic syndrome.
Medchemexpress LLC α-Cyclodextrin | 10016-20-3 | 100.0% | 5 G
α-Cyclodextrin (α-CD) is a soluble fiber derived from corn. It depletes sphingolipids and phospholipids from cell membranes, interacts with tubulin, and improves defenses against SARS-CoV-2 infection. It enhances the anticancer efficacy of Curcumin against breast, lung, and cervical cancer, and has beneficial effects on body weight and blood lipids.
- Exerts a protective effect against SARS-CoV-2 infection in Vero E6 cells
- Enhances the antitumor effect of Curcumin on MCF-7, A549, and HeLa cells
- Diets containing 1-20% α-Cyclodextrin did not produce signs of toxicity or adverse effects in rats (13 weeks)
- Diets containing 0-20% α-Cyclodextrin were well tolerated in Beagle dogs (13 weeks), although diarrhea occurred