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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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DL- -Hydroxyglutaric acid disodium salt (CAS 40951-21-1) is a small molecule analogue of -hydroxyglutaric acid a metabolite implicated in neurometabolic disorders In humans aberrant accumulation of D- -hydroxyglutaric acid occurs in D-2-hydroxyglutaric aciduria associated with mutations in isocitrate dehydrogenase (IDH) enzymes particularly IDH1 and IDH2 These mutations alter normal metabolic flux leading to overproduction of D- -hydroxyglutaric acid from 2-oxoglutarate In preclinical studies elevated levels of this metabolite are detectable in IDH1-mutant glioma models and non-invasive quantification is feasible via magnetic resonance spectroscopy DL- -Hydroxyglutaric acid disodium salt is utilized in research investigating metabolic dysregulation biomarker development and disease mechanisms linked to IDH mutations and gliomagenesis
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Integrin V beta 5 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 8 Protein Human (HEK293 His solution) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 8 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 8 Protein Human (HEK293 His solution) has molecular weight of 187 95 kDa
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Vitamin D binding protein precursor 353-363 is a serum glycoprotein fragment derived from Homo sapiens It is associated with vitamin D binding protein (DBP) a plasma protein that binds vitamin D metabolites and actin monomers mediating transport in the bloodstream and regulation of extracellular actin levels DBP is present on surfaces of various immune cell types including B and T lymphocytes as well as placental cytotrophoblasts Based on these pharmacological properties vitamin D binding protein precursor 353-363 holds research potential in studies of vitamin D metabolism immune regulation and cytoskeletal interactions
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Balsalazide Disodium is the disodium salt form of balsalazide an aminosalicylate and oral prodrug that is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine Balsalazide Disodium suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway
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HyperTrap Heparin FF Column is an affinity chromatography medium designed for the purification of heparin-binding biomolecules The column exploits the strong ionic and specific interactions between immobilized heparin and target proteins such as growth factors coagulation factors and certain enzymes enabling selective retention and efficient separation from complex biological mixtures This tool is widely utilized in the isolation and characterization of heparin-binding proteins investigation of protein glycosaminoglycan interactions and purification of bioactive factors for downstream functional assays and structural analyses
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Beta III Tubulin Antibody (YA4243) is a monoclonal antibody targeting beta III Tubulin. It is also known as tubulin, beta 3; MC1R; and TUBB4. This antibody is reactive with human, mouse, and rat samples.
Suitable for various applications including Western Blot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (FC), and Enzyme-Linked Immunosorbent Assay (ELISA).
Monoclonal antibody with high specificity.
Predicted and observed molecular weight is 50 kDa.
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HyperTrap Heparin FF Column is an affinity chromatography medium designed for the purification of heparin-binding biomolecules The column exploits the strong ionic and specific interactions between immobilized heparin and target proteins such as growth factors coagulation factors and certain enzymes enabling selective retention and efficient separation from complex biological mixtures This tool is widely utilized in the isolation and characterization of heparin-binding proteins investigation of protein glycosaminoglycan interactions and purification of bioactive factors for downstream functional assays and structural analyses
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