Bafilomycin D is a macrolide natural product that acts as a specific inhibitor of vacuolar-type ATPase (V-ATPase). It is employed in biochemical and cell biology research to probe autophagy, endosomal and lysosomal acidification, and proton pump function, and it displays antimicrobial, insecticidal, herbicidal, and cytotoxic activities.
- Specific inhibitor of vacuolar-type ATPase (V-ATPase).
- Used to study autophagy and lysosomal function in cells.
- Causes endosomal and lysosomal deacidification.
- Provided as a high-purity solid suitable for research use.
- Powder stable at -20°C; solutions recommended for -80°C storage for long term.