Lipids and Lipid Derivatives
Apexbio Technology LLC Prednisolone Acetate 52-21-1 250mg
Prednisolone acetate (52-21-1) is a synthetic glucocorticoid derivative targeting glucocorticoid receptors (GR) It is designed to modulate GR-mediated signaling pathways thereby regulating inflammatory and immune response gene expression Prednisolone acetate exerts its biological activity primarily through binding to cytosolic GR forming complexes that translocate into the nucleus to modulate transcriptional events related to inflammation and immune function Based on these pharmacological properties prednisolone acetate holds research potential in the investigation of inflammatory and allergic responses immune regulation and transcriptional modulation in experimental models of chronic inflammation
Selleck Chemical LLC strawberry acid
trans-2-Methyl-2-pentenoic Acid ((E)-2-Methyl-2-pentenoic Acid strawberry acid) has a sweet berry-like aroma and flavor and is widely used in food flavor
Selleck Chemical LLC Alantolactone
Alantolactone a naturally occurring eudesmane-type sesquiterpene lactone (SL) could induce activin/SMAD3 signaling and disrupt Cripto-1/activin receptor type II A interaction
Selleck Chemical LLC FG-2216
FG-2216 is a potent and orally active HIF prolyl 4-hydroxylase inhibitor with IC50 of 3 9 M for PHD2 Phase 2
Avanti Polar Lipids 18:1 Cy5 PE, Chloroform | 2260669-61-0 | 1 mg
18:1 Cy5 PE, Chloroform | Mol Wt: 1260.830 | 2260669-61-0 | 1 mg
Cayman Chemical VItamIn D ELISA MoncLNal n
A phospholipid containing the long-chain saturated fatty acid stearic acid
Apexbio Technology LLC Limonin 1180-71-8 10mM (in 1mL DMSO)
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models