Glycerophospholipids
Invitrogen™ Fluorescein DHPE (N-(Fluorescein-5-Thiocarbamoyl)-1,2-Dihexadecanoyl-sn-Glycero-3-Phosphoethanolamine, Triethylammonium Salt)
Excitation/emission maxima ∽496/519nm
Invitrogen™ NBD-PE (N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)-1,2-Dihexadecanoyl-sn-Glycero-3-Phosphoethanolamine, Triethylammonium Salt)
The phospholipid, NBD-PE is labeled on the head group with the environment sensitive fluorophore, NBD.
Invitrogen™ Bis-BODIPY™ FL C11-PC) (1,2-Bis-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Undecanoyl)-sn-Glycero-3-Phosphocholine)
Dye-labeled phospholipids used to monitor phospholipase A (PLA) activity
Invitrogen™ Oregon Green™ 488 1,2-Dihexadecanoyl-sn-Glycero-3-Phosphoethanolamine (Oregon Green™ 488 DHPE)
With excitation/emission maxima ∽501/526 nm
Invitrogen™ Texas Red™ 1,2-Dihexadecanoyl-sn-Glycero-3-Phosphoethanolamine, Triethylammonium Salt (Texas Red™ DHPE)
The phospholipid, Texas Red™ 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine, triethylammonium salt (Texas Red™ DHPE) is labeled on the head group with the bright, red-fluorescent Texas Red™ dye.
Invitrogen™ Lissamine™ Rhodamine B 1,2-Dihexadecanoyl-sn-Glycero-3-Phosphoethanolamine, Triethylammonium Salt (rhodamine DHPE)
With excitation/emission maxima ∽560/580nm
Invitrogen™ β-BODIPY™ FL C12-HPC (2-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoyl)-1-Hexadecanoyl-sn-Glycero-3-Phosphocholine)
Effective lipid trafficking tracer and general-purpose membrane probes
DLPC 18194-25-7 10mM (in 1mL Ethanol)
DLPC (CAS 18194-25-7) is a synthetic ligand that functions as an agonist of the orphan nuclear receptor liver receptor homolog-1 (LRH-1) LRH-1 is involved in the regulation of bile acid synthesis and through this pathway it modulates glucose and lipid metabolism In cell-based assays DLPC selectively activates human and murine LRH-1 without affecting other nuclear receptors such as FXR CAR PXR or PPAR isoforms DLPC has been shown to induce transcription of genes involved in bile acid biosynthesis and metabolism such as CYP8B1 and modulate promoters like Shp and Oct4 in vitro In murine models DLPC administration increases enzymes for bile acid synthesis reduces hepatic triglycerides and blood glucose and improves glucose homeostasis DLPC is thus a valuable chemical probe for studying LRH-1 function and metabolic regulation in research settings
1-PALMITOYL-SN-GLYCERO-3 500MG
Also available in 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. 1-Palmitoyl-sn-glycero-3-phosphocholine (1-Hexadecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine for fluorescent probe designpurity: 100%
sn-Glycero-3-phosphocholine 28319-77-9 10g
sn-Glycero-3-phosphocholine (CAS 28319-77-9) also known as alpha-GPC or choline alfoscerate is a naturally occurring choline compound found in the brain and mammalian milk It serves as a precursor to acetylcholine a key neurotransmitter involved in cognitive processes by efficiently crossing the blood-brain barrier and supplying choline for neurotransmitter synthesis Preclinical and clinical research has examined its potential to enhance cognitive function particularly in neurodegenerative conditions such as Alzheimer s disease and vascular dementia Clinical studies have reported improved cognitive recovery in post-stroke and dementia patients following alpha-GPC administration supporting its utility in neuropharmacology and cognitive disorder research