Lipids and Lipid Derivatives
Apexbio Technology LLC Sodium butyrate(Synonyms: Butyric acid sodium salt, Sodium n-butyrate, Sodium butanoate, Sodium salt of butyric acid), 10mM (in 1mL H2O), CAS: 156-54-7.
Sodium butyrate (CAS 156-54-7) is a small-molecule inhibitor of histone deacetylases (HDACs) enzymes that regulate gene expression by deacetylating histone proteins By inhibiting HDAC activity sodium butyrate increases histone acetylation levels modifying transcription factor functions and subsequently affecting gene transcription In vitro sodium butyrate promotes apoptosis in colorectal adenoma and carcinoma cell lines (RG/C2 and AA/CI respectively) suggesting anticancer research applications In vivo sodium butyrate administration in transgenic mouse models of Huntington s disease improved survival motor function and mitigated neuropathological damage Thus sodium butyrate is valuable in biomedical research targeting epigenetic regulation and neurodegenerative diseases
Apexbio Technology LLC Abscisic Acid (Dormin)(Synonyms: ABA, Dormin, Abscisin II, (+)-Abscisic acid, (S)-(+)-Abscisic acid, S-Abscisic acid, cis-Abscisic acid), 100mg, CAS: 21293-29-8.
Abscisic acid (Dormin CAS 21293-29-8) is a plant hormone involved in regulating plant growth development and stress responses Its activity includes mediating seed dormancy germination control lateral root formation and adaptive responses to abiotic stress Mechanistically ABA influences histone H2B ubiquitination and chromatin remodeling processes thereby modulating gene expression during seed maturation and under environmental stress ABA signaling also alters cellular redox status by enhancing synthesis of antioxidants such as -tocopherol and L-ascorbate It is widely utilized in plant biology research to study stress physiology developmental biology and epigenetic gene regulation
Sigma Aldrich Fine Chemicals Biosciences Progesterone meets USP testing specifications | 57-83-0 | MFCD00003658 | 5G
Progesterone meets USP testing specifications | Purity: >=97% | Mol Wt: 314.46 | 57-83-0 | MFCD00003658 | 5G
Sigma Aldrich Fine Chemicals Biosciences Progesterone United States Pharmacopeia (USP) Reference Standard | 57-83-0 | MFCD00003658 | 200MG
Progesterone United States Pharmacopeia (USP) Reference Standard | Mol Wt: 314.46 | 57-83-0 | MFCD00003658 | 200MG
Sigma Aldrich Fine Chemicals Biosciences Sodium oleate >=95% (capillary GC) | 143-19-1 | MFCD00004438 | 10G
Sodium oleate >=95% (capillary GC) | Purity: >=95% (capillary GC) | Mol Wt: 304.44 | 143-19-1 | MFCD00004438 | 10G
Sigma Aldrich Fine Chemicals Biosciences Progesterone powder, BioReagent, suitable for cell culture | 57-83-0 | MFCD00003658 | 1g
Progesterone powder, BioReagent, suitable for cell culturePurity: | MW: 314.46 | 57-83-0 | MFCD00003658 | 1g
Sigma Aldrich Fine Chemicals Biosciences Sodium oleate >=99% | 143-19-1 | MFCD00004438 | 10G
Sodium oleate >=99% | Purity: >=99% | Mol Wt: 304.44 | 143-19-1 | MFCD00004438 | 10G
Sigma Aldrich Fine Chemicals Biosciences Progesterone | 57-83-0 | MFCD00003658 | 100 g
Progesterone | Purity: ≥99% | Mol Wt: 314.46 | 57-83-0 | MFCD00003658 | 100 g
Sigma Aldrich Fine Chemicals Biosciences beta-Estradiol 3-benzoate >=97% | 50-50-0 | MFCD00003692 | 200MG
beta-Estradiol 3-benzoate >=97% | Purity: >=97% | Mol Wt: 376.49 | 50-50-0 | MFCD00003692 | 200MG
Sigma Aldrich Fine Chemicals Biosciences 17alpha-Hydroxyprogesterone >=95% | 68-96-2 | MFCD00003659 | 25G
17alpha-Hydroxyprogesterone >=95% | Purity: >=95% | Mol Wt: 330.46 | 68-96-2 | MFCD00003659 | 25G
Sigma Aldrich Fine Chemicals Biosciences beta-Estradiol 3-benzoate >=97% | 50-50-0 | MFCD00003692 | 5G
beta-Estradiol 3-benzoate >=97% | Purity: >=97% | Mol Wt: 376.49 | 50-50-0 | MFCD00003692 | 5G
Sigma Aldrich Fine Chemicals Biosciences Cholic acid from bovine and/or ovine, >=98% | 81-25-4 | MFCD00003672 | 25G
Cholic acid from bovine and/or ovine, >=98% | Purity: >=98% | Mol Wt: 408.57 | 81-25-4 | MFCD00003672 | 25G
Apexbio Technology LLC Catalpol 2415-24-9 20mg
Catalpol (2415-24-9) is a small-molecule modulator targeting adrenal cortical cells It is designed to stimulate steroidogenic pathways thereby promoting androgen hormone secretion Catalpol exerts its biological activity primarily through upregulation of steroid biosynthesis and inhibition of inflammatory mediators In in vitro experiments evaluating steroid hormone biosynthesis catalpol demonstrates an inhibitory activity profile against inflammatory mediators with an IC50 value ranging approximately from 10 to 50 M depending on assay conditions and cell models used Based on these pharmacological properties catalpol holds research potential in adrenal cortex function studies regulation of androgen synthesis pathways and investigations of anti-inflammatory mechanisms
Apexbio Technology LLC Terpinen-4-ol 562-74-3 100mg
Terpinen-4-ol (CAS 562-74-3) is a monoterpene alcohol predominantly found in tea tree oil It exhibits broad-spectrum antimicrobial and anti-inflammatory activities attributed to its ability to disrupt microbial cell membranes and modulate pro-inflammatory mediator expression Terpinen-4-ol has demonstrated acaricidal activity particularly relevant to the ocular parasite Demodex spp Its therapeutic potential is being evaluated in clinical studies including investigations for the treatment of Demodex blepharitis This compound is of interest for research focused on antimicrobial mechanisms and host-pathogen interactions
Apexbio Technology LLC Megestrol Acetate 595-33-5 10mM (in 1mL DMSO)
Megestrol Acetate (CAS 595-33-5) is a synthetic progestin utilized to downregulate nuclear and cytoplasmic androgen receptor activity It modulates hormone receptor-mediated processes thereby impacting cellular metabolic and signaling pathways Megestrol Acetate exerts its biological activity primarily by inducing apoptosis and disrupting cell cycle progression In in vitro studies using HepG2 cell lines Megestrol Acetate demonstrates proliferation inhibition with an IC50 value of approximately 260 M Based on these pharmacological properties Megestrol Acetate holds research potential in studies of cancer cachexia hepatocellular carcinoma and the investigation of tumor growth mechanisms