Nucleosides and Analogues
Apexbio Technology LLC 2-Amino-ATP(Synonyms: 2-NH2-ATP, 2-Aminoadenosine triphosphate, 2-Amino-adenosine-5'-triphosphate, 2-Amino-ATP (free acid)), 50ul (100 mM).
2-Amino-ATP is a modified nucleotide structurally related to ATP (adenosine triphosphate) featuring an amino substitution at the adenine ring s 2-position It acts as an ATP analog capable of competitively binding at the active sites of ATP-dependent enzymes potentially modulating their enzymatic activity and influencing downstream signaling pathways In research settings 2-Amino-ATP serves as a molecular tool to examine substrate specificity mechanistic aspects of ATP-binding enzymes (e g kinases and ATPases) and nucleotide-dependent receptor interactions facilitating studies of nucleotide signaling and cellular metabolism
Research Products International Corp 5-Bromo-2'-Deoxyuridine, 5 Grams
Thymidine analog used for study of DNA synthesis. This analog selectively incorporates into cellular DNA during S-phase. Supplied as white powder.
Medchemexpress LLC Adenosine receptor antagonist 2 | 2703054-47-9 | 99.37% | C23H21FN8O | 50 MG
Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC50s of 1 nM and 3 nM, respectively. It has anti-tumor activity.
- Orally active A2a/A2b adenosine receptor antagonist
- IC50s of 1 nM (A2a) and 3 nM (A2b)
- Anti-tumor activity
Apexbio Technology LLC UDP disodium salt(Synonyms: Uridine 5'-diphosphate disodium salt, Uridine diphosphate disodium salt, UDP-Na2), 10mM (in 1mL H2O), CAS: 27821-45-0.
UDP disodium salt (CAS 27821-45-0) is a selective agonist targeting the P2Y6 receptor exhibiting potent stimulatory activity with an EC50 value of approximately 300 nM and a reported pEC50 of 6 52 for the human P2Y6 receptor Endogenously UDP serves as a metabolite involved in catalyzing glucuronidation reactions facilitating the conjugation of glucuronic acid to diverse substrates Due to these biological properties UDP disodium salt finds utility in researching disease-related mechanisms and RNA biosynthesis pathways
[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O | 100mg | 525183198](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000130440.jpg-250.jpg)
eMolecules 1094-61-7 | ??-Nicotinamide mononucleotide | Ambeed | MFCD00038748 | 334.221 | C11H15N2O8P | 97.000 | NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O | 100mg | 525183198
??-Nicotinamide mononucleotide | Ambeed | 1094-61-7 | MFCD00038748 | 334.221 | C11H15N2O8P | 97.000 | NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O | 100mg | 525183198
Medchemexpress LLC Guanosine 5'-triphosphate-5'-adenosine triammonium | 99.97% | 823.50 | 25 MG
Guanosine 5'-triphosphate-5'-adenosine (GpppA) triammonium is a 5' cap analog that can be used for RNA synthesis in vitro. It is also described as a fluorescent substrate analog.
- Fluorescent substrate analog.
- Can be used for RNA synthesis in vitro.
- Acts as an artificial substrate when labeled with pyrene at the 3′-O position of adenosine.
- Fluorescently labeled GpppA triammonium and GpppG analogs are potential substrates that balance structural complexity and enzymatic requirements.
Medchemexpress LLC Α,β-methylene-ATP trisodium | 1343364-54-4 | 99.0% | 571.15 | 1 ML
Α,β-methylene-ATP trisodium | 1343364-54-4 | 99.0% | 571.15 | 1 ML
Medchemexpress LLC 2'-Deoxyuridine (standard) | 951-78-0 | 99.15% | 50 MG
2'-Deoxyuridine (standard) | 951-78-0 | 99.15% | 50 MG
Medchemexpress LLC Etidronic acid disodium | 7414-83-7 | 98.0% | 1 ML
Etidronic acid disodium is an orally and intravenously active bisphosphonate. It inhibits bone resorption, reduces arterial calcification, and can be used for osteoporosis research. It also exhibits anticancer activity and acts as a chelating agent to remove heavy metals from water.
- Inhibits bone resorption
- Reduces arterial calcification
- Can be used for osteoporosis research
- Possesses anticancer activity
- Functions as a chelating agent to remove heavy metals in water
Apexbio Technology LLC 8-Azido-ATP(Synonyms: 8-Azidoadenosine 5'-triphosphate, 8-N3-ATP, 8-Azido-ATP, 8-Azidoadenosine triphosphate), 50ul (100 mM).
8-Azido-ATP is a ribonucleoside triphosphate analog with an azido group substitution at the adenine C-8 position It acts primarily as an ATP mimic interacting with poly(A) polymerase (PAP) specifically illustrated using yeast poly(A) polymerase (yPAP) Incorporation of 8-azido-ATP into growing polyadenylation chains results in premature termination and moderately shorter poly(A) tails relative to natural ATP substrates Due to its chain-terminating capacity and altered substrate specificity 8-azido-ATP is applied in biochemical studies examining enzyme fidelity nucleotide selection mechanisms and RNA polymerase activity
Apexbio Technology LLC 7-Deaza-ATP(Synonyms: 7-Deazaadenosine triphosphate, 7-Deaza-ATP, 7-Deazaadenosine-5'-triphosphate), 10ul (100 mM).
7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
![eMolecules 114248-23-6 | 2'-Deoxy-2',2'-difluorouridine | AA Blocks LLC | MFCD00871912 | 264.185 | C9H10F2N2O5 | 0.000 | OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C(F)(F)[C@@H]1O | 100mg | 447933339](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3962532.jpg-250.jpg)
eMolecules 114248-23-6 | 2'-Deoxy-2',2'-difluorouridine | AA Blocks LLC | MFCD00871912 | 264.185 | C9H10F2N2O5 | 0.000 | OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C(F)(F)[C@@H]1O | 100mg | 447933339
2'-Deoxy-2',2'-difluorouridine | AA Blocks LLC | 114248-23-6 | MFCD00871912 | 264.185 | C9H10F2N2O5 | 0.000 | OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C(F)(F)[C@@H]1O | 100mg | 447933339
Medchemexpress LLC Recombinant human adenosine kinase | >95.0% | 50 UG
Recombinant human adenosine kinase (ADK) is a full-length, tag-free enzyme produced in HEK293 cells for biochemical and enzymatic research. Supplied as a filtered solution with stabilizers, it offers consistent activity and low endotoxin for reliable assay results.
- Full-length human sequence (M1-H345).
- Expressed in HEK293 mammalian cells for native folding.
- Tag free to minimize assay interference.
- Purity >95% as determined by reducing SDS-PAGE.
- Formulated in 20 mM Tris, 300 mM NaCl, pH 8.0, with stabilizers and 20% glycerol.
- Endotoxin <1 EU/μg and measured specific activity for activity-based assays.
- Supplied as a frozen solution and shipped on dry ice to preserve activity.
Medchemexpress LLC GTP-14564 | 34823-86-4 | 99.9% | 234.25 | 50 MG
GTP-14564 is a tyrosine kinase inhibitor that targets internal tandem duplication (ITD) and FLT3. It inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells. It is a potential research tool for studying FLT3-related leukemia.
- Tyrosine kinase inhibitor
- Targets internal tandem duplication (ITD)
- Targets FLT3
- Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells
- Appearance: solid
- Color: off-white to yellow