Nucleosides and Analogues
Sigma Aldrich Fine Chemicals Biosciences Guanosine 98500G
Guanosine is an aromatic organic molecule and a purine nucleoside. It is present in the cerebrospinal fluid intestinal cells blood-brain barrier and in brain microvessels.
SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES 2-DEOXYADENOSINE 5-TRIPHOSPH
NC3835281 2-DEOXYADENOSINE 5-TRIPHOSPH
Medchemexpress LLC 7-Methyl-guanosine-5'-triphosphate sodium | 5 MG
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. Its phosphorothioate analog is a potent cap-dependent translation inhibitor.
- Potent cap-dependent translation inhibitor.
Apexbio Technology LLC N6-Methyl-ATP 50ul (100 mM)
N6-Methyl-ATP is a methylated derivative of adenosine triphosphate (ATP) designed to function as a selective agonist for purinergic P2 receptors Due to structural modifications including methylation at the N6 position of the adenine moiety this compound displays specificity for interaction with distinct subtypes of P2 purinergic receptors In cellular and molecular research N6-Methyl-ATP is utilized as a pharmacological tool to investigate receptor-mediated signaling pathways particularly ion channel activation calcium influx and associated intracellular signaling cascades modulated through P2 receptors Furthermore it serves as a molecular probe in characterizing purinergic receptor-mediated neurotransmission physiological regulatory processes and receptor subtype distribution in both normal physiological states and pathological conditions contributing to the foundational understanding necessary for receptor-targeted drug discovery
Apexbio Technology LLC 7-Deaza-ATP(Synonyms: 7-Deazaadenosine triphosphate, 7-Deaza-ATP, 7-Deazaadenosine-5'-triphosphate), 10ul (100 mM).
7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
Sigma Aldrich Fine Chemicals Biosciences Flavin adenine dinucleotide disodium salt hydrate >=95% (HPLC), powder | 84366-81-4 (anhydrous) | MFCD08277021 | 250MG
Flavin adenine dinucleotide disodium salt hydrate >=95% (HPLC), powder | Purity: >=95% (HPLC) | 84366-81-4 (anhydrous) | MFCD08277021 | 250MG
Medchemexpress LLC Α,β-methylene-ATP trisodium | 1343364-54-4 | 99.0% | 571.15 | 1 ML
Α,β-methylene-ATP trisodium | 1343364-54-4 | 99.0% | 571.15 | 1 ML
Medchemexpress LLC Mtb ATP synthase-IN-1 | 2642394-38-3 | 98.6% | C17H13N3O4 | 10MG
Mtb ATP synthase-IN-1 is a potent Mycobacterium tuberculosis ATP synthase inhibitor (compound 6ab) for anti-mycobacterial research. It exhibits MIC 0.452-0.499 μg/mL against M. tuberculosis, demonstrates good metabolic stability and acceptable oral bioavailability, and shows low cytotoxicity in Vero cells.
- Potent inhibition of M. tuberculosis ATP synthase
- MIC 0.452-0.499 μg/mL against M. tuberculosis
- Good metabolic stability
- Low cytotoxicity (Vero IC50 > 64 μg/mL)
- High purity (~98.6%)
- Available in multiple solid and solution pack sizes
- Stable storage recommendations for powder and solutions
Medchemexpress LLC Aica-riboside, 5'-phosphate | 3031-94-5 | MFCD00057264 | 100.0% | C9H15N4O8P | 10MG
AICA-riboside, 5′-phosphate is the 5′-phosphorylated form of AICA-riboside that functions as an AMP mimetic and activator of AMP-activated protein kinase (AMPK). It is provided as a high-purity solid for biochemical and cellular research into metabolic and neurological pathways.
- Acts as an AMP mimetic and activates AMP-activated protein kinase.
- Provided as a high-purity solid suitable for biochemical studies.
- Molecular formula C9H15N4O8P and molecular weight 338.21 g·mol⁻¹.
- Available in small quantities for experimental use.
- Commonly used in metabolic disease and neuroprotection research.
Medchemexpress LLC Adenosine amine congener (ADAC) | 96760-69-9 | 99.23% | 25 MG
Adenosine amine congener (ADAC) is a selective A1 adenosine receptor agonist. It can ameliorate noise- and cisplatin-induced cochlear injury and demonstrates neuroprotective effects.
- Selective A1 adenosine receptor agonist
- Ameliorates noise- and cisplatin-induced cochlear injury
- Has neuroprotective effects
- Reduces oxidative stress in noise-exposed cochlea
- Protects sensory hair cells
- Reduces cisplatin-induced apoptosis in cochlear tissues
- Inhibits glutamate release via presynaptic A1 receptors
- Inhibits voltage-gated Ca2+ channels
- Mitigates noise-induced hearing loss in a dose- and time-dependent manner