Nucleosides and Analogues
Medchemexpress LLC Desethyl chloroquine diphosphate | 247912-76-1 | MFCD28138115 | 99.7% | 487.81 | C16H28ClN3O8P2 | 5 MG
Desethyl chloroquine diphosphate is the diphosphate salt of desethyl chloroquine supplied as a research reagent and analytical standard. It is provided as a high-purity solid intended for biochemical, pharmacological, and analytical applications, with documentation including a data sheet and safety data sheet.
- High purity suitable for analytical work (reported 99.7%).
- Diphosphate salt form for improved solubility and stability.
- Molecular weight 487.81 and formula C16H28ClN3O8P2 for accurate calculations.
- Available in small milligram pack sizes for reference and method development.
- Supplied with datasheet and SDS for handling and compliance.
Selleck Chemical LLC Primaquine Diphosphate S4237-50mg
Primaquine Diphosphate is a transmission-blocking anti-malarial clinically available displaying a marked activity against gametocytes of all species of human malaria
Cambridge Isotope Laboratories ADENOSINE 13C10 98 1SN10MG
Adenosine (13C10, 98%; 1sN5, 96-98%), 10mg
Medchemexpress LLC Motesanib diphosphate | 857876-30-3 | MFCD12407403 | 99.9% | 569.44 | C22H29N5O9P2 | 25 MG
Motesanib diphosphate is a small-molecule, ATP-competitive inhibitor of vascular endothelial growth factor receptors VEGFR1, VEGFR2, and VEGFR3 that also inhibits Kit. The diphosphate salt is supplied for research and analytical applications.
- Potent VEGFR1/2/3 inhibition (IC50 ~2 nM, 3 nM, 6 nM).
- Also inhibits Kit, with ~10-fold selectivity for VEGFR versus PDGFR and Ret.
- High purity (≈99.86%) with molecular weight 569.44 and formula C22H29N5O9P2.
- Supplied as a 25 mg research/analytical sample.
- Intended for non-clinical, research use only.
Apexbio Technology LLC Motesanib Diphosphate (AMG-706) 857876-30-3 10mM (in 1mL DMSO)
Motesanib Diphosphate (AMG-706 CAS 857876-30-3) is an oral small-molecule ATP-competitive inhibitor that targets vascular endothelial growth factor receptors (VEGFR1/2/3) platelet-derived growth factor receptor (PDGFR) c-Kit and Ret with reported IC50 values of 2 84 nM It demonstrates over 1000-fold selectivity for VEGFRs relative to EGFR Src and p38 kinases In vitro Motesanib Diphosphate potently inhibits VEGF-induced proliferation of human endothelial cells (IC50 10 nM) and blocks PDGF- and SCF-induced signaling while showing minimal effects on bFGF-stimulated proliferation In preclinical studies it suppresses angiogenesis and induces regression in tumor xenograft models Motesanib is under investigation in anti-angiogenic cancer research
Medchemexpress LLC AZT triphosphate tet 1mg | 106060-92-8 | 1 MG
AZT triphosphate tetraammonium is the tetraammonium salt of the active triphosphate metabolite of zidovudine (AZT). Supplied as an off-white to light yellow solid, it is used as a biochemical reagent and reference standard in studies of viral polymerase activity and nucleotide metabolism.
- Active triphosphate metabolite of zidovudine with antiretroviral activity.
- Supplied as a stable solid suitable for biochemical assays and standards.
- High purity (99.25%) to support analytical and research applications.
- Store sealed at -20°C; in solution store at -80°C for long-term stability.
- Available in small quantities (for example, 1 mg) and larger sizes for research use.
Selleck Chemical LLC BRM/BRG1 ATP Inhibitor-1
BRM/BRG1 ATP Inhibitor-1 (Compound 14) is an orally active inhibitors of Brahma Homolog (BRM)/SMARCA2 (BRG1) with IC50s below 0 005 M
Selleck Chemical LLC Adenosine S1647-10mM/1mL
Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a -N9-glycosidic bond
![Alkali Scientific Adenosine, Free Base [9 β D Ribofuranosyladenine], 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661074.jpg-250.jpg)
Alkali Scientific Adenosine, Free Base [9 β D Ribofuranosyladenine], 5 G
Adenosine, Free Base [9 β D Ribofuranosyladenine], 5 G is a specialized reagent used in biochemical and molecular biology research. This nucleoside is essential for the study of cellular energy metabolism and signal transduction pathways. Adenosine plays a vital role in the production of ATP, RNA, and DNA. It is widely used in assays that explore nucleotide metabolism, enzyme kinetics, and cell signaling mechanisms. As a fundamental building block for cellular functions, it is used in research on diseases like cancer, heart disease, and neurodegenerative conditions, where nucleotide metabolism is altered or dysregulated.
Medchemexpress LLC Guanosine 5'-diphosphate-13C10 dilithium | 98.7% | 461.97 | 1 MG
Guanosine 5'-diphosphate-13C10 (GDP-13C10) dilithium is a 13C-labeled nucleoside diphosphate. It activates adenosine 5'-triphosphate-sensitive K+ channels and acts as a potential iron mobilizer, preventing hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway. This compound is used in inflammation research, including anemia of inflammation (AI).
- Activates adenosine 5'-triphosphate-sensitive K+ channels.
- Acts as a potential iron mobilizer.
- Prevents hepcidin-ferroportin interaction.
- Modulates the interleukin-6 (IL-6)/stat-3 pathway.
- Utilized in inflammation research, including anemia of inflammation (AI).
- Functions as a tracer for quantitative analysis.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes like 13C for drug development quantitation.
Medchemexpress LLC Guanosine 5'-(trihydrogen diphosphate), monosodium salt | 43139-22-6 | 99.9% | 465.18 | 1 G
Guanosine 5'-(trihydrogen diphosphate), monosodium salt | 43139-22-6 | 99.9% | 465.18 | 1 G
Medchemexpress LLC Adenosine A1 receptor activator T62 | 40312-34-3 | 98.9% | 291.80 g/mol | C15H14ClNOS | 1 ML
Adenosine A1 receptor activator T62 is a selective positive allosteric modulator of the adenosine A1 receptor supplied for in vitro research. It is available as a solid or as a ready-to-use 10 mM solution in DMSO, with reported purity of 98.93% and a molecular weight of 291.80 g/mol. Follow the SDS for storage and safe handling.
- Allosteric enhancer of adenosine A1 receptor.
- Available as solid or 10 mM solution in DMSO.
- High reported purity suitable for biochemical and cellular assays.
- High solubility in DMSO (100 mg/mL) for easy formulation.
- Multilingual SDS provided for safety and handling guidance.
