Nucleosides and Analogues
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 50 MG
2'-deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product is a precursor in the synthesis of Edoxudine and an analogue of 5-ethynyl-2'-deoxyuridine, EdU. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Brain-penetrant pyrimidines nucleotide
- Associated with nervous system diseases
- Increases chromosome breakage
- Decreases thymidylate synthetase activity
- Reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury
- Promising for Alzheimer's disease (AD) research
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.2% | 100 MG
2'-Deoxyuridine | 951-78-0 | 99.2% | 100 MG
Medchemexpress LLC Tenofovir diphosphate disodium | 2738719-07-6 | 99.42% | 491.14 | 1 MG
Tenofovir diphosphate disodium is an antiretroviral agent primarily used for AIDS research. It acts as an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM). This compound exhibits minimal inhibitory effect on eukaryotic DNA replication in vitro.
- Antiretroviral agent
- Inhibits HIV reverse transcriptase DNA and RNA
- Used for AIDS research
- Minimal inhibitory effect on eukaryotic DNA replication in vitro
![eMolecules 74804-12-9 | Adenosine 5'-triphosphate magnesium salt | Combi-Blocks | MFCD00084767 | 529.470 | C10H14MgN5O13P3 | 95.000 | [Mg++].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O | 1g | 388718358](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502212903.JPG-250.jpg)
eMolecules 74804-12-9 | Adenosine 5'-triphosphate magnesium salt | Combi-Blocks | MFCD00084767 | 529.470 | C10H14MgN5O13P3 | 95.000 | [Mg++].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O | 1g | 388718358
Adenosine 5'-triphosphate magnesium salt | Combi-Blocks | 74804-12-9 | MFCD00084767 | 529.470 | C10H14MgN5O13P3 | 95.000 | [Mg++].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O | 1g | 388718358
Sigma Aldrich Fine Chemicals Biosciences Coenzyme A Trilithium Salt | ≥85% Purity | Mol Wt: 767.5 | ®93-18-4-3 | 10 mg
Coenzyme A trilithium salt | Purity: ≥85% | Mol Wt: 767.5 | CAS No: 93-18-4-3 | Biochemical cofactor involved in metabolic pathways and energy production via acyl transfer and thioesterification | 10mg
Medchemexpress LLC Glucosamine | 3416-24-8 | ≥98.0% | 50 MG
Glucosamine (D-Glucosamine; Chitosamine) is an amino sugar that serves as a precursor in the biochemical synthesis of glycosylated proteins and lipids, used as a dietary supplement. It is a natural component of glycosaminoglycans found in the cartilage matrix and synovial fluid. When administered externally, it has pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Appearance: Solid, white to off-white
- Molecular weight: 179.17
- Formula: C6H13NO5
- Structure classification: Saccharides, monosaccharides
- Initial source: Endogenous metabolite, human gut microbiota metabolites, microorganisms
Cayman Chemical 6-ChloropurIn RIbosIde 1g
A nucleoside precursor; used in the synthesis of adenosine or N6-benzyladenosine derivatives with anticancer or antiparasitic activities in vitro
Medchemexpress LLC Adenosine 5'-triphosphate dimagnesium | 74804-12-9 | 98.0% | 500 MG
ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo, providing metabolic energy to drive metabolic pumps and serving as a coenzyme in cells. It is also an important endogenous signaling molecule in immunity and inflammation.
- Synergistically activates the NLRP3 inflammasome in HGFs when co-treated with LPS.
- Induces secretion of IL-1β, KC, and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.
- Promotes neutrophil chemotaxis in vitro.
- Protects mice against bacterial infection in vivo.
- Induces the secretion of IL-1β, KC, and MIP-2 and neutrophils recruitment in vivo.
Medchemexpress LLC Ribavirin-13C5 | 1646818-35-0 | 1 MG
Ribavirin-13C5 is a 13C-labeled version of Ribavirin, an antiviral agent effective against a wide range of viruses including HCV, HIVl, and RSV. This compound is intended for research use only.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
eMolecules 58-96-8 | Uridine | Apollo Scientific | MFCD00006526 | 244.203 | C9H12N2O6 | 99.000 | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O | 25g | 562424027
Uridine | Apollo Scientific | 58-96-8 | MFCD00006526 | 244.203 | C9H12N2O6 | 99.000 | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O | 25g | 562424027
![eMolecules 34369-07-8 | Adenosine 5'-triphosphate disodium salt hydrate from microbial source, min. 99% (HPLC) | Oakwood Chemicals567.145 | C10H14N5Na2O14P3 | 99.000 | O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O | 1g | 480154085](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502143415.JPG-250.jpg)
eMolecules 34369-07-8 | Adenosine 5'-triphosphate disodium salt hydrate from microbial source, min. 99% (HPLC) | Oakwood Chemicals567.145 | C10H14N5Na2O14P3 | 99.000 | O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O | 1g | 480154085
Adenosine 5'-triphosphate disodium salt hydrate from microbial source, min. 99% (HPLC) | Oakwood Chemicals | 34369-07-8567.145 | C10H14N5Na2O14P3 | 99.000 | O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O | 1g | 480154085
Medchemexpress LLC Adenosine receptor antagonist 2 | 2703054-47-9 | 99.4% | C23H21FN8O | 100 MG
Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist. It exhibits anti-tumor activity by inhibiting tumor growth in vivo. This compound is characterized by its potent inhibitory concentrations for both A2a and A2b adenosine receptors.
- Orally active A2a/A2b adenosine receptor antagonist
- IC50 of 1 nM for A2a adenosine receptor
- IC50 of 3 nM for A2b adenosine receptor
- Exhibits anti-tumor activity
- Inhibits tumor growth in female C57BL/6 mice
- Demonstrates specific pharmacokinetic profiles in mice studies