Nucleosides and Analogues
Sigma Aldrich Fine Chemicals Biosciences alpha-Nicotinamide adenine dinucleotide from Saccharomyces cerevisiae, <=1% beta-isomer, >=95% | 7298-93-3 | MFCD00134828 | 10MG
alpha-Nicotinamide adenine dinucleotide from Saccharomyces cerevisiae, <=1% beta-isomer, >=95% | Purity: >=95% | Mol Wt: 663.43 | 7298-93-3 | MFCD00134828 | 10MG
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5'-triphosphate disodium salt hydrate BioXtra, >=99% (HPLC), from microbial | 34369-07-8 | MFCD00150755 | 10G
Adenosine 5'-triphosphate disodium salt hydrate BioXtra, >=99% (HPLC), from microbial | Purity: >=99% (HPLC) | 34369-07-8 | MFCD00150755 | 10G
Apexbio Technology LLC 7-Deaza-ATP(Synonyms: 7-Deazaadenosine triphosphate, 7-Deaza-ATP, 7-Deazaadenosine-5'-triphosphate), 10ul (100 mM).
7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
Medchemexpress LLC NBI-961 (formerly CMP3a) | 2225902-98-5 | 99.7% | 568.61 g/mol | C28H27F3N6O2S | 10 MG
NBI-961 is a potent NEK2 inhibitor that inhibits proteasomal degradation and induces G2/mitosis arrest and apoptosis in diffuse large B cell lymphoma (DLBCL) cells. It is supplied as a solid, light yellow to yellow research-use-only compound and is available in small amounts for laboratory studies.
- High purity (99.7%).
- Molecular weight 568.61 g/mol.
- Chemical formula C28H27F3N6O2S.
- Soluble in DMSO at 100 mg/mL (requires ultrasonic).
- Powder storage: -20°C for 3 years; 4°C for 2 years.
- Intended for laboratory research use only; not for human or animal use.
Cambridge Isotope Laboratories ADENOSINE 13C10 98 1SN10MG
Adenosine (13C10, 98%; 1sN5, 96-98%), 10mg
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5′-triphosphate sodium salt hydrate | 36051-31-7 | MFCD00077781 | 25mg
Guanosine 5′-triphosphate sodium salt hydrate | 36051-31-7 | MFCD00077781 | 25mg
eMolecules Chem-Impex b-Nicotinamide mononucleotide 250mg 490843765 33732 0 000 1094-61-7 334 221 C11H15N2O8P
Chem-Impex b-Nicotinamide mononucleotide 250mg 490843765 33732 0 000 1094-61-7 334 221 C11H15N2O8P
Medchemexpress LLC 2-Deoxyadenosine 5 10mM 1mL
2 -Deoxyadenosine 5 -monophosphate disodium a nucleic acid AMP derivative is a deoxyribonucleotide found in DNA 2 -Deoxyadenosine 5 -monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1]
Apexbio Technology LLC 7-Deaza-ATP(Synonyms: 7-Deazaadenosine triphosphate, 7-Deaza-ATP, 7-Deazaadenosine-5'-triphosphate), 100ul (100 mM).
7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
Medchemexpress LLC Adenosine 5'-triphosphate | 56-65-5 | 99.9% | 5 G
ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. It provides metabolic energy for pumps and acts as a coenzyme in cells. ATP is also an important endogenous signaling molecule in immunity and inflammation, capable of activating the NLRP3 inflammasome and inducing IL-1β and chemokine secretion. It exhibits anti-bacterial infection effects and can protect mice against bacterial infection.
- Provides metabolic energy and acts as a coenzyme
- Functions as an important endogenous signaling molecule in immunity and inflammation
- Activates the NLRP3 inflammasome
- Induces IL-1β and chemokine secretion
- Exhibits anti-bacterial infection effects
- Protects against bacterial infection in mice
- Synergistically activates the NLRP3 inflammasome with LPS in HGFs
- Induces secretion of IL-1β, KC, and MIP-2 from BMDMs
- Promotes neutrophil chemotaxis
Medchemexpress LLC 2'-deoxyadenosine | 958-09-8 | MFCD00005754 | 99.9% | 251.24 | C10H13N5O3 | 25 MG
2'-deoxyadenosine is an analytical standard of the adenine nucleoside 2'-deoxyadenosine supplied for research and analytical use. It inhibits glucose-stimulated insulin release and cAMP accumulation, activates caspase-3 to promote apoptosis, and shows antiproliferative effects in some cell models. It is intended for use as a reference in HPLC, GC, and MS methods and is not for human use.
- Analytical standard for HPLC, GC, and MS applications.
- High purity, 99.9% (as supplied in COA).
- CAS number 958-09-8 for unambiguous identification.
- Molecular formula C10H13N5O3; molecular weight 251.24.
- Available in small pack sizes suitable for method development and reference standards.
Cayman Chemical RIbavIrIn-13C5 1mg
An internal standard for the quantification of ribavirin by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences alpha-Nicotinamide adenine dinucleotide from Saccharomyces cerevisiae, <=1% beta-isomer, >=95% | 7298-93-3 | MFCD00134828 | 250MG
alpha-Nicotinamide adenine dinucleotide from Saccharomyces cerevisiae, <=1% beta-isomer, >=95% | Purity: >=95% | Mol Wt: 663.43 | 7298-93-3 | MFCD00134828 | 250MG
Medchemexpress LLC Uridine-1',2',3',4',5'-13C5 | 159496-16-9 | 99.9% | 249.16 g/mol | C4(13C)5H12N2O6 | 10 MG
Uridine-13C5 is a stable isotope-labeled form of the nucleoside uridine with five 13C-enriched carbon atoms. It is supplied as a research-grade solid intended for use as an internal standard or tracer in metabolic labeling and mass spectrometry applications.
- Purity 99.9%.
- Physical form off-white to light brown solid.
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Intended for use as an internal standard or tracer in metabolic and mass spectrometry studies.
- Available in small packaging sizes, including 10 mg.
- CAS number 159496-16-9; molecular weight 249.16 g/mol.