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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that is utilized in the synthesis of PROTACs. PROTACs themselves are small molecules composed of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
Application: used in the synthesis of PROTACs.
Mechanism: facilitates the degradation of target proteins via the ubiquitin-proteasome system when incorporated into PROTACs.
Research use: for research purposes only; not intended for sale to patients.
Form: liquid (density: 1.252 g/cm3), colorless to light yellow.
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Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent containing an Azide group, enabling it to participate in various cycloaddition reactions. PROTACs are designed to degrade target proteins via the intracellular ubiquitin-proteasome system.
Utilized in the synthesis of PROTACs
Functions as a click chemistry reagent
Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups
Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Br-PEG3-MS is a brominated, PEG-based PROTAC linker (methanesulfonate) designed for use in chemical synthesis of PROTACs and other bifunctional molecules. It provides a short PEG3 spacer with a reactive leaving group for conjugation chemistry, enabling efficient formation of linkages between ligands under standard organic conditions. For research use only.
PEG3 spacer with a terminal bromide and methanesulfonate leaving group.
Suitable for linker synthesis and nucleophilic substitution reactions.
High purity (95.0% by NMR) for reliable synthetic performance.
Low molecular weight facilitates handling in small-scale reactions.
Available in multiple small pack sizes to support medicinal chemistry workflows.
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N-(Azido-PEG3)-N-bis(PEG4-acid) is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This compound acts as a click chemistry reagent, featuring an Azide group. It can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions when combined with Alkyne groups. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Functions as a click chemistry reagent
Contains an Azide group
Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups
Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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Fmoc-NH-PEG3-CH2CH2COOH is an Fmoc-protected PEG3-based cleavable linker used for conjugation chemistry in research applications such as antibody-drug conjugates and PROTAC synthesis. It provides a short PEG spacer with an Fmoc-protected amino terminus and a terminal carboxylic acid for coupling reactions.
High purity suitable for research use.
PEG3 spacer provides solubility and flexibility.
Fmoc protection enables standard amine deprotection workflows.
Terminal carboxylic acid allows amide bond formation.
Available in multiple pack sizes for synthesis scale-up.
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Atrovastatin-PEG3-FITC is a fluorescently labeled atorvastatin derivative used as a ligand/tracer to study KRAS-PDEδ interactions. It is applied in fluorescence anisotropy and related binding assays to characterize protein-ligand interactions and support biochemical screening and biophysical analysis.
Fluorescent FITC label suitable for anisotropy and fluorescence assays.
Acts as a ligand for studying KRAS-PDEδ interactions.
High purity (98.17%).
Molecular weight 1150.31; formula C64H68FN5O12S.
DMSO soluble at 100 mg/mL; ultrasonic assistance and freshly opened DMSO recommended.
Available in small research pack sizes (for example, 5 mg).
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More