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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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OSI-930 (CAS 728033-96-3) is a small molecule inhibitor targeting multiple receptor tyrosine kinases including Flt1 (IC 8 nM) KDR/VEGFR2 (IC 9 nM) CSF-1R (IC 15 nM) Lck c-Raf and Kit (IC 80 nM) In cellular studies OSI-930 inhibits proliferation and induces apoptosis in HMC-1 cells whose survival is dependent on Kit signaling while exhibiting minimal effects on COLO-205 cells under standard conditions Additionally OSI-930 inactivates cytochrome P450 3A4 in a time- and concentration-dependent manner and alters its spectral properties These characteristics make OSI-930 a valuable tool compound for investigating receptor tyrosine kinase signaling pathways and related cellular processes in cancer research
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(S)-1-(4-(Trifluoromethoxy)phenyl)ethanamine is a drug intermediate for the synthesis of various active compounds. It is for research use only and not sold to patients.
Appearance: Solid-liquid mixture
Color: Colorless to off-white
Shipping: Room temperature in continental US; may vary elsewhere
Storage: 4°C, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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