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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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D-Ribofuranose-13C5 (D-Ribose-13C5) is the 13C-labeled D-Ribofuranose (HY-113375) D-Ribofuranose (D-Ribose) is an endogenous metabolite present in Cerebrospinal Fluid that can be used for the research of Ribose 5 Phosphate Isomerase Deficiency and Medium Chain Acyl Co A Dehydrogenase Deficiency[1][2]
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DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). It features a DBCO group, which facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Non-cleavable 3 unit PEG ADC linker.
Used in the synthesis of antibody-drug conjugates (ADCs).
Contains a DBCO group.
Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups.
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Calcein tetraethyl ester is a fluorescent dye used in biology. It can be transported through the cellular membrane into live cells, which makes it useful for testing of cell viability and for short-term labeling of cells.
Fluorescent dye.
Can be transported through the cellular membrane.
Useful for testing cell viability.
Useful for short-term labeling of cells.
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Fluorescein dilaurate is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate. It is for research use only.
Has a molecular weight of 696.91
Formula is C44H56O7
Appears as a solid
Color is white to off-white
Ships at room temperature in continental US, may vary elsewhere
Store at 4°C, protect from light
In solvent, store at -80°C for 6 months or -20°C for 1 month, protect from light
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Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Pomalidomide-based cereblon ligand and a linker used in PROTAC technology.
Synthesized E3 ligase ligand-linker conjugate
Incorporates Pomalidomide-based cereblon ligand
Used in PROTAC technology
Targets Cereblon
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NH-bis(PEG3-azide) is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
PEG-based PROTAC linker
Click chemistry reagent
Contains an Azide group
Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups
Capable of strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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m-PEG5-Br is a PEG-based PROTAC linker. It is for research use only and not for sale to patients. This linker can be used in the synthesis of PROTACs, which consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Used in the synthesis of PROTACs
Utilizes the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
For research use only
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Pancuronium dibromide (CAS 15500-66-0) is a small molecule that acts as a competitive antagonist at nicotinic acetylcholine receptors (AChRs) blocking neuromuscular transmission by displacing acetylcholine from its binding sites on the motor end-plate This action results in skeletal muscle relaxation characterized by dose-dependent neuromuscular blockade With an IC50 value of approximately 5 5 nM pancuronium dibromide serves as a potent pharmacological tool for studying cholinergic receptor function neuromuscular signaling pathways and muscle physiology in biomedical research
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