Organometallic Compounds
ILEX LIFE SCIENCES LLC PAN Biotech CMRL 1066 Cell Culture Medium without L Glutamine without Phenol Red GMP Grade 500 ML 1/EA
PAN-Biotech CMRL 1066 Cell Culture Medium w/o L-Glutamine w/o Phenol red w 2 2 g/L NaHCO3 GMP Grade 500 ml DESCRIPTION CMRL-1066 GMP Grade is a ready-to-use chemically-defined medium designed for direct use in GMP-regulated clinical and industrial applications It provides a precisely controlled formulation that supports stable and reproducible cell culture performance Combined with high batch-to-batch consistency controlled quality parameters and comprehensive documentation CMRL-1066 GMP is a true ready-to-use medium suitable for sensitive development scale-up and manufacturing workflows QUALITY GMP Grade (EU Annex 1) BICARBONATE With 2 2 g/L Sodium Bicarbonate GLUCOSE With glucose GLUTAMINE No Glutamine HEPES Without HEPES LIQUID/POWDER Liquid PHENOL RED Without Phenol Red SODIUM PYRUVATE Without Sodium Pyruvate STERILE Yes STORAGE 2 C - 8 C MANUFACTURER PAN-Biotech GmbH COUNTRY OF ORIGIN Germany
Medchemexpress LLC RGD Trifluoroacetate | 2378808-45-6 | 99.55% | 460.36 | 5 MG
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines, and elicits specific cell responses. It is the most effective and often used peptide sequence for stimulated cell adhesion on synthetic surfaces, with 24 integrins binding to ECM molecules in an RGD-dependent manner.
- Binds to integrins
- Triggers cell adhesion
- Addresses certain cell lines
- Elicits specific cell responses
Medchemexpress LLC Calcein (tetraethyl ester) | 1170856-93-5 | 99.5% | 5 MG
Calcein tetraethyl ester, also known as Fluorexon tetraethyl ester, is a fluorescent dye utilized in biological applications. Its key characteristic is its ability to be transported through the cellular membrane into live cells. This property makes it valuable for assessing cell viability and for the short-term labeling of cells.
- Effective for live cell studies: Its cell-permeable nature allows for direct application in living systems without damaging cell integrity.
- Versatile in research: Can be used for various analyses including cell function, in vivo imaging, and cell staining.
Medchemexpress LLC RGD (Trifluoroacetate) | 2378808-45-6 | 99.55% | 460.36 | 25 MG
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion and elicits specific cell responses by binding to integrins. It is the most effective and most often employed peptide sequence for stimulated cell adhesion on synthetic surfaces.
- Triggers cell adhesion
- Binds to integrins
- Most effective peptide for stimulated cell adhesion
- Suitable for laboratory centrifugation and storage
Medchemexpress LLC RGD (Trifluoroacetate) | 2378808-45-6 | 99.6% | 460.36 | 100 MG
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines, and elicits specific cell responses. It binds to integrins and is the most effective and commonly used peptide sequence for stimulated cell adhesion on synthetic surfaces. This product is intended for research use only.
- Triggers cell adhesion
- Addresses certain cell lines
- Elicits specific cell responses
- Binds to 24 integrins in an RGD-dependent manner, including α3β1, α5β1, α8β1, αIIbβ3, αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, and to some extent α2β1 and α4β1
Medchemexpress LLC Calcein (tetraethyl ester) | 1170856-93-5 | 99.5% | 25 MG
Calcein tetraethyl ester is a fluorescent dye utilized in biology for evaluating cell viability and facilitating short-term cellular labeling. Its ability to permeate cellular membranes allows for transport into live cells.
- Fluorescent dye for biological applications
- Enables cell viability testing
- Suitable for short-term cell labeling
- Permeates live cell membranes
- Useful in cell staining analysis
- Applied in in vivo imaging fluorescence
Medchemexpress LLC Calcein (tetraethyl ester) | 1170856-93-5 | >99.5% | 1 ML
Calcein tetraethyl ester is a fluorescent dye used in biology. It can be transported through the cellular membrane into live cells, which makes it useful for testing of cell viability and for short-term labeling of cells.
- Fluorescent dye.
- Can be transported through the cellular membrane.
- Useful for testing cell viability.
- Useful for short-term labeling of cells.
Medchemexpress LLC Abemaciclib (methanesulfonate) | 1231930-82-7 | 99.8% | 602.70 | 200 MG
This compound is a selective and BBB-permeable inhibitor of CDK4/6, with half-maximal inhibitory concentrations (IC50s) of 2 nM and 10 nM for CDK4 and CDK6, respectively.
- Selective inhibition of key enzymes involved in cell cycle regulation.
- Permeates the blood-brain barrier.
- Reduces cell viability in various human cell lines, including HCT-116, MCF7, and PANC-1.
- Inhibits Rb phosphorylation, leading to a G1 arrest and suppressed proliferation.
- Activity is specific for cells that are proficient in Rb.
- Effective in reducing cell viability across multiple cancer cell lines.
- Demonstrates antiproliferative activity against human HCT116 and MCF7 cells.
- Shows inhibition in resistant cell lines.
- Causes a cooperative antitumor effect when combined with other agents in xenograft models.
- Leads to significant tumor growth inhibition in xenograft models.
Medchemexpress LLC Methotrexate hydrate | 133073-73-1 | MFCD00150847 | 99.57% | C20H24N8O6 | 5 G
Methotrexate hydrate, also known as Amethopterin hydrate, is a chemical compound primarily recognized for its role in affecting cell growth and division. This substance is widely utilized in medical applications, particularly in the treatment of various cancers and autoimmune diseases. Its mechanism of action involves inhibiting the process by which cells synthesize DNA, thereby controlling proliferation.
- Affects cell growth and division
- Used to fight certain diseases, especially cancer and autoimmune diseases
- Works by inhibiting DNA synthesis in cells
Medchemexpress LLC Methotrexate hydrate | 133073-73-1 | ≥99.0% | C20H22N8O5.xH2O | 25 G
Methotrexate hydrate is a substance that affects cell growth and division. It is commonly used to fight certain diseases, especially cancer and autoimmune diseases, by inhibiting the process by which cells synthesize DNA. As a biochemical reagent, it can be utilized as a biological material or organic compound for life science-related research.
- Affects cell growth and division
- Commonly used in cancer and autoimmune disease research
- Inhibits DNA synthesis in cells
- Can be used as a biochemical reagent for life science research
Apexbio Technology LLC IDE 1 1160927-48-9 1mg
IDE 1 (CAS 1160927-48-9) is a small-molecule compound designed to promote differentiation of stem cells toward the definitive endoderm lineage by activating receptors involved in the TGF- signaling pathway IDE 1 exerts its biological activity primarily through activation of the TGF- signaling pathway In in vitro studies IDE 1 induces definitive endoderm specification from pluripotent stem cells Based on these pharmacological properties IDE 1 holds research potential in in vitro differentiation protocols to generate endoderm-derived cells such as hepatocytes and pancreatic cells and in studies investigating early embryonic lineage commitment and regenerative medicine
Apexbio Technology LLC IDE 1 1160927-48-9 10mg
IDE 1 (CAS 1160927-48-9) is a small-molecule compound designed to promote differentiation of stem cells toward the definitive endoderm lineage by activating receptors involved in the TGF- signaling pathway IDE 1 exerts its biological activity primarily through activation of the TGF- signaling pathway In in vitro studies IDE 1 induces definitive endoderm specification from pluripotent stem cells Based on these pharmacological properties IDE 1 holds research potential in in vitro differentiation protocols to generate endoderm-derived cells such as hepatocytes and pancreatic cells and in studies investigating early embryonic lineage commitment and regenerative medicine