Organometallic Compounds
Medchemexpress LLC Gemigliptin tartrate | 1374639-74-3 | 99.5% | 639.45 | 5 MG
Gemigliptin tartrate is a highly selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC50 of 10.3 nM for human recombinant DPP-4. It exhibits potent anti-glycation properties and can be used for the research of advanced glycation end products (AGE)-related diabetic complications. This product is for research use only.
- Highly selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor
- IC50 of 10.3 nM for human recombinant DPP-4
- Exhibits potent anti-glycation properties
- Useful for research of advanced glycation end products (AGE)-related diabetic complications
- Dose-dependently inhibits the formation of AGE-BSA
- Suppresses the cross-linking of preformed AGE-BSA with rat tail tendon collagen
- Inhibits AGEs formation and AGE cross-links in vivo
- Dose-dependently inhibits plasma DPP-4 activity in various animal models
Medchemexpress LLC Gemigliptin (tartrate) | 1374639-74-3 | 99.5% | 639.45 | 1 ML
Gemigliptin tartrate, also known as LC15-0444 tartrate, is a highly selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor with an IC50 of 10.3 nM for human recombinant DPP-4. It demonstrates potent anti-glycation properties and can be used in research concerning advanced glycation end products (AGE)-related diabetic complications.
- Highly selective DPP-4 inhibitor.
- Exhibits potent anti-glycation properties.
- Useful for research on AGE-related diabetic complications.
- Dose-dependently inhibits AGE-BSA formation.
- Suppresses cross-linking of preformed AGE-BSA.
Medchemexpress LLC Gemigliptin tartrate hydrate | 1375415-82-9 | 99.8% | 666.49 | 5 MG
Gemigliptin tartrate hydrate is a selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor with an IC50 of 10.3 nM for human recombinant DPP-4. It exhibits potent anti-glycation properties and can be used for the research of advanced glycation end products (AGE)-related diabetic complications.
- Selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor
- Exhibits potent anti-glycation properties
- Useful for research of advanced glycation end products (AGE)-related diabetic complications
Medchemexpress LLC Gemigliptin tartrate hydrate | 1375415-82-9 | 99.8% | 666.49 | 25 MG
Gemigliptin tartrate hydrate is a selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor. It exhibits potent anti-glycation properties and can be used for the research of advanced glycation end products (AGE)-related diabetic complications.
- Selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor
- Exhibits potent anti-glycation properties
- Used for research of advanced glycation end products (AGE)-related diabetic complications
- IC50 of 10.3 nM for human recombinant DPP-4
Medchemexpress LLC Gemigliptin tartrate hydrate | 1375415-82-9 | 99.8% | 666.49 | 100 MG
Gemigliptin (LC15-0444) tartrate hydrate is a selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC50 of 10.3 nM for human recombinant DPP-4. It exhibits potent anti-glycation properties and can be used for the research of advanced glycation end products (AGE)-related diabetic complications.
- Selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor
- Exhibits potent anti-glycation properties
- Used for the research of advanced glycation end products (AGE)-related diabetic complications
Medchemexpress LLC Gemigliptin tartrate hydrate | 1375415-82-9 | 99.8% | 666.49 | 50 MG
Gemigliptin tartrate hydrate is a selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor. It exhibits potent anti-glycation properties, making it suitable for research into advanced glycation end products (AGE)-related diabetic complications. This product is intended for research use only.
- Selective, reversible, and competitive DPP-4 inhibitor
- Potent anti-glycation properties
- Suitable for research of AGE-related diabetic complications
- Appears as a white to off-white solid
- For research use only
Medchemexpress LLC Gemigliptin (tartrate) | 1374639-74-3 | 99.5% | 639.45 | 25 MG
Gemigliptin tartrate is a highly selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC50 of 10.3 nM for human recombinant DPP-4. It also shows potent anti-glycation properties and can be used for research on advanced glycation end products (AGE)-related diabetic complications.
- Highly selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor
- IC50 of 10.3 nM for human recombinant DPP-4
- Exhibits potent anti-glycation properties
- Can be used for the research of advanced glycation end products (AGE)-related diabetic complications
Medchemexpress LLC 5,7,4'-Trimethoxyflavone | 5631-70-9 | 1 ML
5,7,4'-Trimethoxyflavone (MTF) is a compound isolated from the medicinal plant *Kaempferia parviflora*. It acts as a CFTR activator and demonstrates diverse biological activities, including inducing apoptosis and exhibiting antitumor properties. This compound can also help prevent skin aging and oxidative stress.
- CFTR activator with an EC50 of 64 μM
- Induces apoptosis in SNU-16 cells
- Increases proteolytic activation of caspase-3
- Degrades ADP-ribose polymerase (PARP) protein
- Exhibits antitumor activity
- Helps prevent skin aging and oxidative stress
- Inhibits cell proliferation and TNF-α induced ROS
Medchemexpress LLC 5,7,4'-Trimethoxyflavone | 5631-70-9 | 25 MG
5,7,4'-Trimethoxyflavone can be isolated from the medicinal plant Kaempferia parviflora (KP). It acts as a CFTR activator with an EC50 of 64 μM, induces apoptosis, and increases the proteolytic activation of caspase-3. This compound also causes the degradation of ADP-ribose polymerase (PARP) protein, exhibits antitumor activity, and can be used to prevent skin aging and oxidative stress.
- CFTR activator with an EC50 of 64 μM
- Induces apoptosis
- Increases proteolytic activation of caspase-3
- Causes degradation of ADP-ribose polymerase (PARP) protein
- Exhibits antitumor activity
- Prevents skin aging and oxidative stress
- Isolated from the medicinal plant Kaempferia parviflora
Medchemexpress LLC 5,7,4'-Trimethoxyflavone | 5631-70-9 | 50 MG
5,7,4'-Trimethoxyflavone (MTF) can be isolated from the medicinal plant Kaempferia parviflora. It acts as a CFTR activator and induces apoptosis by increasing proteolytic activation of caspase-3 and degrading ADP-ribose polymerase (PARP) protein. This compound also exhibits antitumor activity and can be used to prevent skin aging and oxidative stress. In vitro studies have shown its ability to inhibit cell proliferation and induce apoptosis in SNU-16 cells, as well as its anti-inflammatory and anti-oxidative effects in HDFs cells.
- Isolated from the medicinal plant Kaempferia parviflora.
- Acts as a CFTR activator with an EC50 of 64 μM.
- Induces apoptosis, increases proteolytic activation of caspase-3, and degrades PARP protein.
- Exhibits antitumor activity.
- Prevents skin aging and oxidative stress.
- Demonstrated cytotoxicity in SNU-16 cells.