Aminosaccharides
Chem-Impex International, Inc. 4-Methylumbelliferyl-N-acetyl-b-D-galactosaminide | 36476-29-6 | MFCD00067658 | 250MG
4-Methylumbelliferyl-N-acetyl-b-D-galactosaminide, 36476-29-6, MFCD00067658, 250MG
Medchemexpress LLC Azidoethyl-SS-PEG2-Boc | 2144777-83-1 | 351.49 | 1 G
Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Peg-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group for CuAAc and SPAAC reactions
- For research use only
Medchemexpress LLC Azidoethyl-SS-PEG2-Boc | 2144777-83-1 | 351.49 | 50 MG
Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Peg-based protac linker
- Click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- For research use only
Medchemexpress LLC Azidoethyl-SS-PEG2-Boc | 2144777-83-1 | 351.49 | 250 MG
Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
- PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC D(+)-Galactosamine hydrochloride | 1772-03-8 | 99.9% | 215.63 | 100 MG
D(+)-Galactosamine hydrochloride | 1772-03-8 | 99.9% | 215.63 | 100 MG
Medchemexpress LLC D(+)-Galactosamine hydrochloride | 1772-03-8 | 99.9% | 215.63 | 1 G
D(+)-Galactosamine hydrochloride is an established experimental toxin known to primarily cause liver injury by generating free radicals and depleting UTP nucleotides. It also induces renal dysfunction, often leading to renal failure associated with end-stage liver damage. This compound can be used to induce hepatitis models, mimicking viral hepatitis by causing lipid peroxidation and cell membrane deterioration.
- Induces apoptosis and necrosis in primary cultures of rat hepatocytes.
- Causes caspase-3 activation and DNA fragmentation.
- Used as an animal model for fulminant hepatic failure.
- Induces acute liver failure in mice when co-administered with Lipopolysaccharide.
Sigma Aldrich Fine Chemicals Biosciences N-Acetyl-D-galactosamine | 1811-31-0 | MFCD00065372 | 1g
N-Acetyl-D-galactosamine | Purity: 98% | Mol Wt: 221.21 | 1811-31-0 | MFCD00065372 | 1g
Medchemexpress LLC O-Linked GlcNAc transferase substrate | 954381-93-2 | 98.25% | 1783.08 | 10 MG
O-Linked GlcNAc transferase substrate is a biologically active peptide that functions as a substrate for O-linked GlcNAc transferase (OGT), a eukaryotic glycosyltransferase that utilizes UDP-GlcNAc as a glycosyl donor.
- Biological active peptide
- Substrate of O-linked GlcNAc transferase (OGT)
- White to off-white solid appearance
- High purity of 98.25%
- Soluble in DMSO and H2O at 100 mg/mL
- Sequence: Lys-Lys-Lys-Tyr-Pro-Gly-Gly-Ser-Thr-Pro-Val-Ser-Ser-Ala-Asn-Met-Met