Monosaccharides
Selleck Chemical LLC Disodium
Disodium (R)-2-Hydroxyglutarate (D- -Hydroxyglutaric acid disodium) is a competitive inhibitor of -ketoglutarate-dependent dioxygenases with Ki of 10 87 1 85 mM
TARGETMOL CHEMICALS INC Dazostinag disodium 1MG
Also available in 5 mg, 25 mg and bulk. Please contact Fisher for quotes. Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist that triggers STING signaling pathway activation and type I interferon activation. Dazostinag disodium (TAK-676) is also a highly effective immune system modulator with complete resolution and lasting memory of T cell immunity and the ability to promote lasting interferon-dependent anti-tumor immune responses. Purity 99.96%
Selleck Chemical LLC Disodium Cromoglycate S1911-50mg
Disodium Cromoglycate (Gynazole FPL 670 (Cromolyn) Disodium Cromolyn sodium) is an antiallergic drug with IC50 of 39 g/mL
Selleck Chemical LLC NADH Disodium Salt Hydrate
NADH is a coenzyme that functions as a regenerating electron donor in catabolic processes including glycolysis -oxidation and the citric acid cycle
Selleck Chemical LLC Eosin Y Disodium
Eosin Y is a form of eosin It is most commonly used as an acidic red stain for highlighting cytoplasm material in samples
Medchemexpress LLC USP7 Ligand-Linker Conjugates 1 | 671.83 | 25MG
USP7 Ligand-Linker Conjugates 1 is a Target Protein Ligand-Linker Conjugate designed for the synthesis of PROTAC USP7 Degrader-1. This product incorporates a ligand for USP7 and a PROTAC linker, which recruits E3 ligases. PROTACs operate by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is intended for use as laboratory chemicals and in the manufacture of substances for research purposes only, to be handled by suitably qualified and experienced scientists in appropriately equipped and authorized facilities.
- Incorporates a ligand for USP7
- Recruits E3 ligases
- Used for the synthesis of PROTAC USP7 Degrader-1
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
TARGETMOL CHEMICALS INC SIGMA-LIGAND-1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM 19 nM at the DTG site and the PPP site respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor. purity: 100%
Sigma Aldrich Fine Chemicals Biosciences Glucose 6 phosphate Dehydr
Glucose 6-phosphate dehydrogenase (G-6-P-DH) is a key regulatory enzyme in the first step of the pentose phosphate pathway. G-6-P-DH is a glycoprotein with a molecular mass of 128 kDa (gel filtration).
Medchemexpress LLC GDP-D-mannose disodium | 103301-73-1 | 10 MG
GDP-D-mannose disodium is an endogenous metabolite consisting of GDP-α-D-mannose and GDP-β-D-mannose. GDP-α-D-mannose acts as the donor substrate for mannosyltransferases and serves as the precursor for GDP-β-L-fucose. It exhibits competitive inhibition with respect to GTP and uncompetitive inhibition with respect to mannose-1-P. This product is intended for research use only.
- Comprises GDP-α-D-mannose and GDP-β-D-mannose
- Donor substrate for mannosyltransferases
- Precursor for GDP-β-L-fucose
- Exhibits competitive inhibition with GTP (Ki 14.7 μM)
- Exhibits uncompetitive inhibition with mannose-1-P (Ki 115 μM)
- Molecular weight: 649.30
- Chemical formula: C16H23N5Na2O16P2
- Appearance: Solid, white to off-white
- Classified as an endogenous metabolite
Sigma Aldrich Fine Chemicals Biosciences Glucose-6-phosphate Dehydr
Glucose 6-phosphate dehydrogenase (G-6-P-DH) is a key regulatory enzyme in the first step of the pentose phosphate pathway. G-6-P-DH is a glycoprotein with a molecular mass of 128 kDa (gel filtration).
Medchemexpress LLC K-Ras ligand-linker conjugate 6 | 00-00-0 | C42H60N8O7 | 10MG
K-Ras ligand-linker conjugate 6 is a research-grade ligand-linker conjugate intended for K-Ras targeting and PROTAC development. Supplied as a solid for biochemical and cellular research, it has formula C42H60N8O7, molecular weight 788.98 g·mol⁻¹, and CAS 2378261-89-1. Store dry under inert gas at -20°C; in solvent store at -80°C for up to 6 months.
- Designed for K-Ras targeting in PROTAC and ligand-linker studies.
- Suitable for biochemical and cellular research applications.
- Provided in multiple milligram-scale quantities for flexible dosing.
- Characterized by molecular formula C42H60N8O7 and MW 788.98 g·mol⁻¹.
- Includes datasheet and safety data sheet for handling and storage guidance.
Medchemexpress LLC Cromolyn (disodium) | 15826-37-6 | 100.0% | 25 MG
Cromolyn disodium is an orally active GSK-3β inhibitor (IC50 of 2.0 μM) and a mast cell stabilizer. It inhibits mediator release from mast cells, regulates reflex bronchoconstriction, and reduces non-specific bronchial hyperreactivity. Primarily used in bronchial asthma research, it also demonstrates anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective activities. This product is for research use only.
- Orally active GSK-3β inhibitor
- Mast cell stabilizer
- Inhibits mediator release from mast cells
- Regulates reflex bronchoconstriction
- Reduces non-specific bronchial hyperreactivity
- Used in bronchial asthma research
- Demonstrates anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective activities
- For research use only
Apexbio Technology LLC Carbenoxolone disodium 7421-40-1 10mM (in 1mL DMSO)
Carbenoxolone disodium (CAS 7421-40-1) is a small-molecule inhibitor targeting 11 -hydroxysteroid dehydrogenase (11 -HSD) It is designed to modulate glucocorticoid metabolism by suppressing the interconversion of corticosteroid hormones thereby regulating glucocorticoid access to steroid receptors Carbenoxolone disodium exerts its biological activity through inhibition of 11 -HSD enzymatic function In vitro studies demonstrate inhibitory activity with reported IC50 values ranging from 10 30 M depending on experimental conditions and target tissue Based on these pharmacological properties Carbenoxolone disodium holds research potential in neuroendocrine and cardiovascular studies exploring glucocorticoid-mediated signaling pathways
Medchemexpress LLC NSC-87877 (disodium) | 56932-43-5 | 98.0% | 503.42 | 50 MG
NSC-87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases, with IC50 values of 0.318 μM and 0.355 μM for Shp2 and Shp1, respectively. It also inhibits dual-specificity phosphatase 26 (DUSP26).
- Potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases
- Inhibits dual-specificity phosphatase 26 (DUSP26)
- Inhibits DUSP26 function in NB cell lines
- Results in increased p53 phosphorylation and activation
- Possesses excellent anti-neuroblastoma activity in vivo