Sugar acids and derivatives
Medchemexpress LLC 4-Methylumbelliferyl-β-D-glucuronide hydrate | 881005-91-0 | 99.92% | 100 MG
4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrate (λex=362 nm, λem=445 nm). It has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli. It is highly soluble in DMSO (150 mg/mL) and moderately soluble in H2O (5.2 mg/mL), requiring sonication for dissolution.
- Fluorogenic substrate with specific excitation and emission wavelengths
- Detects activity of β-glucuronidase
- Used for detecting Escherichia coli
- High solubility in DMSO
- Requires sonication for dissolution in water
Medchemexpress LLC D-Glucuronic acid (Standard) | 6556-12-3 | 100 MG
D-Glucuronic acid (Standard) is an analytical standard intended for research and analytical applications. It is a significant component of numerous anti-inflammatory proteoglycans, contributing to embryonic development and inhibiting cell aggregation. When metabolized into ethyl glucuronide, it activates Toll-like receptor 4 (TLR4), which is associated with pain. Furthermore, D-Glucuronic acid and its derivative, glucurono-lactone, are known as liver detoxifiers and its derivatives also exhibit anti-tumor activity.
- Analytical standard for assays
- Intended for research and analytical use
- Utilized in HPLC, GC, and MS research experiments
- Major component of anti-inflammatory proteoglycans
- Promotes embryonic development
- Inhibits cell aggregation
- Acts as a liver detoxifier
- Derivatives possess anti-tumor activity
- Solid, white to off-white appearance
- Purity of 99.93%
Medchemexpress LLC β-D-glucuronide-pNP-carbonate | 894095-98-8 | MFCD31715405 | 99.6% | 913.83 | C45H43N3O18 | 250 MG
β-D-glucuronide-pNP-carbonate is a cleavable glucuronide-based carbonate linker used as a precursor in antibody-drug conjugate (ADC) synthesis. It features a p-nitrophenyl (pNP) activated carbonate that facilitates conjugation and enzymatic payload release upon glucuronidase cleavage. Supplied as a white to off-white solid with high purity and defined molecular properties, it is intended for research applications.
- Cleavable glucuronide-based ADC linker for payload release
- Activated p-nitrophenyl carbonate handle for efficient conjugation
- High purity (99.6%) suitable for research applications
- Molecular weight 913.83 and formula C45H43N3O18
- Store at -20°C, sealed and protected from moisture
Ambeed 2R 3R 4S 5S 6S 2Bromo6 methox
(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate, 21085-72-3, 97%
Medchemexpress LLC Diethylstilbestrol-d3 | 58322-36-4 | ≥98% | C18H17D3O2 | 25MG
Diethylstilbestrol-d3 is deuterium labeled Diethylstilbestrol. It is for research use only and can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation during drug development.
- Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 100 MG
Glucuronic acid sodium is a polysaccharide that shows anti-inflammatory activity, aids in the healing of ulcerative colitis, and improves the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. It also helps modulate gut microbiota by increasing beneficial bacterial populations and suppressing harmful ones.
- Exhibits anti-inflammatory activity
- Supports healing of ulcerative colitis
- Enhances intestinal barrier by upregulating tight junction proteins (ZO-1, Occludin)
- Modulates gut microbiota by increasing beneficial bacteria and suppressing harmful ones
Medchemexpress LLC Complement factor D-IN-2 | 1903742-34-6 | 99.33% | 574.43 | 25 MG
Complement factor D-IN-2 is an inhibitor of complement factor D, extracted from patent WO2015130838A1, compound 190. It targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway, and can be used for the research of autoimmune diseases.
- Reduces the excessive activation of complement factor D.
- Targets factor D and inhibits the complement cascade.
- Suitable for research of autoimmune diseases.
- For research use only.
Medchemexpress LLC Cimiracemoside D | 290821-39-5 | MFCD28411517 | 99.9% | 678.85 | C37H58O11 | 10 MG
Cimiracemoside D is a natural glycoside isolated from the plant Actaea racemosa and supplied as a high-purity research reagent. It is characterized by molecular formula C37H58O11, molecular weight 678.85, and CAS number 290821-39-5. The compound is offered as a solid and in DMSO solution formats for laboratory use.
- High purity (99.9%).
- Natural source: Actaea racemosa.
- Molecular formula C37H58O11, molecular weight 678.85.
- Available in solid form and as 10 mM DMSO solutions.
- Intended for research use only.
Ambeed 2R 3R 4S 5S 6S 2Bromo6 methox
(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate, 21085-72-3, 97%
Medchemexpress LLC CDK1/Cyc B-IN-1 | 2459916-56-2 | 98.5% | 353.85 | 100 MG
CDK1/Cyc B-IN-1 is a selective inhibitor of the CDK1/Cyc B complex with an IC50 of 97 nM. It induces apoptosis and G2/M cell cycle arrest, demonstrating broad-spectrum cytotoxic action against various cancer cell lines.
- Selective inhibitor of CDK1/Cyc B complex
- Induces apoptosis
- Causes G2/M cell cycle arrest
- Exhibits broad-spectrum cytotoxic action against cancer cell lines
- Available in various quantities
- Recommended storage conditions for powder and in solvent
- Soluble in DMSO