Sugar acids and derivatives
Medchemexpress LLC Bet-in-19 | 1643947-30-1 | 99.7% | 333.39 | C19H19N5O | 10MG
BET-IN-19 is a small-molecule BET bromodomain inhibitor provided as a high-purity research reagent for epigenetic and oncology studies. It is supplied as a powder in multiple pack sizes and displays cellular activity against AML MV4-11 cells, supporting biochemical and cell-based assays. Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- High purity (99.74%).
- Molecular formula C19H19N5O; molecular weight 333.39.
- Demonstrated inhibition of hIL-6 transcription and c-myc activity (IC50 ≤ 0.3 μM).
- Available in multiple pack sizes for flexible experimental design.
- Supplied as a powder with defined cold-storage stability.
Medchemexpress LLC UDP-glucuronic acid trisodium | 63700-19-6 | 250 MG
UDP-glucuronic acid trisodium is a vital precursor for essential glycoconjugates found across various biological kingdoms, including mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. Intended for research use only, this white to off-white solid has a high purity of 99.87%, a molecular weight of 646.23, and a chemical formula of C15H19N2Na3O18P2.
- Critical precursor for glycoconjugates
- High purity of 99.87%
- Promotes migration of liver cancer cells (Huh7, SK-Hep1, SNU449) by inducing EMT process in vitro
- Decreases E-cadherin levels and increases vimentin levels in Huh7 and SNU449 cells at 0.5 mM in vitro
Medchemexpress LLC CMP-Sialic acid (sodium salt) | 1007117-62-5 | 90.8% | 636.43 | 25 MG
CMP-Sialic acid sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. It provides a substrate for Golgi sialyltransferases and is an important sugar nucleotide for the biosynthesis of sialic acid and its conjugates.
- Allosteric inhibitor of UDP-GlcNAc 2-epimerase.
- Provides a substrate for Golgi sialyltransferases.
- Important sugar nucleotide for biosynthesis of sialic acid and its conjugates.
- Appearance: Solid, white to off-white.
- Can be used as a CMAH substrate to detect the formation of Neu5Gc in platelet lysates (at 22.5 μM for 45 min).
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
Gold Biotechnology Inc NADH Beta Reduced Sodium Salt
Reduced -nicotinamide adenine dinucleotide (NADH) plays a major role in metabolism as a cofactor in redox reactions and as a mobile electron carrier NADH is a high energy compound that donates electrons to the electron transport chain to provide energy for ATP production by oxidative phosphorylation NADH is a required oxidizing cosubstrate in fermentation which regenerates NADH is fluorescent which provides for a relatively simple way to detect NADH in biological samples NADH is also used in enzyme cycling assays to detect relevant biological molecules in tissues
Sigma Aldrich Fine Chemicals Biosciences Polygalacturonic acid | 25990-10-7 | MFCD00131972 | 25g
Polygalacturonic acid | Purity: 85% | 25990-10-7 | MFCD00131972 | 25g
Sigma Aldrich Fine Chemicals Biosciences Alginic acid from brown algae | 9005-32-7 | MFCD00081309 | 100G
Alginic acid from brown algae | 9005-32-7 | MFCD00081309 | 100G
Chem-Impex International, Inc. N-Acetylneuraminic acid | 131-48-6 | MFCD00006620 | 1G
N-Acetylneuraminic acid, 131-48-6, MFCD00006620, 1G