Sugar acids and derivatives
Medchemexpress LLC 5-bromo-4-chloro-3-indolyl β-D-glucuronide sodium salt | 129541-41-9 | MFCD00135782 | 98.0% | 444.59 g/mol | C14H12BrClNNaO7 | 10 MG
X-Gluc sodium is the sodium salt of 5-bromo-4-chloro-3-indolyl β-D-glucuronide, a chromogenic substrate used to detect β-glucuronidase (GUS) activity. It reacts with GUS to produce an intense blue color and is commonly used in microbiology and molecular biology assays.
- Chromogenic substrate for β-glucuronidase detection
- Produces intense blue color upon enzymatic hydrolysis
- Suitable for bacterial contamination testing and GUS reporter assays
- High purity (98.0%) for reliable experimental results
- Sodium salt form improves handling and aqueous solubility
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | 96.4% | 897.90 g/mol | C42H47N3O17S | 250 MG
MAC glucuronide linker-1 is a cleavable ADC linker designed for antibody-agent conjugations and provided for research use. The product is supplied with analytical documentation and recommended storage conditions appropriate for synthesis and conjugation workflows.
- Cleavable ADC linker for antibody-agent conjugation.
- CAS number: 2222981-71-5.
- Molecular weight: 897.90 g/mol.
- Chemical formula: C42H47N3O17S.
- Purity (LCMS): 96.36%.
- Documentation: certificate of analysis and safety data sheet available.
- Recommended storage: 4°C under nitrogen; in solvent -80°C (6 months) or -20°C (1 month).
- Available in multiple packaging sizes, including 250 mg.
Sigma Aldrich Fine Chemicals Biosciences Polygalacturonic acid | 25990-10-7 | MFCD00131972 | 25g
Polygalacturonic acid | Purity: 85% | 25990-10-7 | MFCD00131972 | 25g
Apexbio Technology LLC Cyclosporin D 63775-96-2 25mg
Cyclosporin D (CAS 63775-96-2) is a structural analogue of Cyclosporin A with comparatively reduced immunosuppressive activity Mechanistically it weakly inhibits lymphocyte proliferation induced by mitogens such as PHA PWM PMA and Ca 2 and suppresses Ca 2 /calmodulin-dependent phosphorylation of elongation factor 2 (EF-2) in mouse pancreatic cells In preclinical models Cyclosporin D overcomes Adriamycin resistance in multidrug-resistant ovarian cancer cells and inhibits TPA-induced ear edema and alkaline phosphatase activity in mice Additionally it displays inhibitory effects on the growth of malarial parasites both in vitro and in vivo Cyclosporin D serves as a standard in Cyclosporin A quantification and as a research tool in immunology oncology and antiparasitic studies
Apexbio Technology LLC Beta-Lapachone 4707-32-8 10mg
Beta-Lapachone (CAS 4707-32-8) is a small molecule inhibitor of DNA topoisomerase I In DNA unwinding assays beta-Lapachone suppresses topoisomerase I-mediated DNA relaxation at concentrations as low as 1 M without inhibiting topoisomerase II or inducing topoisomerase I-dependent DNA cleavage It exhibits broad cytotoxicity against human cancer cell lines such as AD2780s HT-29 DLD G480 and MCF-7 with IC50 values ranging from 2 to 5 M The compound induces cell death through cytochrome c release triggering both apoptosis and necrosis and affects cell cycle progression causing S-phase and G2/M arrest in different carcinoma cell models Beta-Lapachone is widely utilized in studies investigating topoisomerase I inhibition cancer cell cytotoxicity and cell cycle regulation
Medchemexpress LLC 4-methylumbelliferyl alpha-L-arabinofuranoside | 77471-44-4 | MFCD00057308 | 99.9% | C15H16O7 | 10MG
4-Methylumbelliferyl alpha-L-arabinofuranoside is a fluorogenic glycosidase substrate used to measure α-L-arabinofuranosidase activity. Enzymatic cleavage releases the fluorescent reporter 4-methylumbelliferone, enabling sensitive fluorometric assays for enzyme kinetics, inhibitor screening, and biochemical studies.
- Fluorogenic substrate for α-L-arabinofuranosidase assays.
- Releases 4-methylumbelliferone for high-sensitivity fluorometric detection.
- Suitable for enzyme kinetics, inhibitor screening, and activity profiling.
- High purity improves assay reproducibility and signal-to-noise ratio.
- Available in small, research-scale quantities for laboratory use.
Medchemexpress LLC Interferon alpha/beta receptor 1 Antibody (YA3833) | 110-130 kDa | 10 UL
This Interferon alpha/beta receptor 1 Antibody (YA3833) is a mouse-derived, non-conjugated IgG1 monoclonal antibody targeting Interferon alpha/beta receptor 1. It forms a heterodimeric receptor with IFNAR2 for type I interferons, activating the JAK-STAT signaling cascade to regulate interferon-responsive genes.
- Mouse-derived monoclonal antibody
- Non-conjugated IgG1 isotype
- Targets interferon alpha/beta receptor 1
- Reacts with human and mouse species
- Suitable for WB, IHC-P, FC, and ELISA applications
- Supplied as a liquid in PBS with 0.05% sodium azide
- Purity is affinity purified
- Store at -20°C for one year; avoid repeated freeze/thaw cycles
![Alkali Scientific 4 Methylumbelliferyl 2 acetamido 2 deoxy B D glucopyranoside [4 Methylumbelliferyl N acetyl B D glucosaminide], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660605.jpg-250.jpg)
Alkali Scientific 4 Methylumbelliferyl 2 acetamido 2 deoxy B D glucopyranoside [4 Methylumbelliferyl N acetyl B D glucosaminide], 1 G
Methylumbelliferyl N-acetylglucosaminide (1 g) is a fluorogenic substrate used in enzymatic assays, particularly for detecting the activity of β-glucosaminidases. This compound is widely used in research and diagnostic laboratories for assessing enzyme activity in microbial samples, tissue cultures, and various biochemical processes. The fluorogenic property of this substrate means it generates a detectable fluorescence when cleaved by the enzyme, providing a sensitive and reliable measurement. This 1 g quantity is ideal for routine laboratory assays where the activity of glycosidases, particularly in cell-based systems, is being studied.
Medchemexpress LLC Sesamolin | 526-07-8 | 99.8% | 370.35 | C20H18O7 | 10 MG
Sesamolin is a lignan isolated from Sesamum indicum with antioxidative and neuroprotective activity. It inhibits lipid peroxidation and suppresses MAPK cascade signaling by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3; oral activity has been reported. The compound is supplied as a solid and as DMSO solutions and is typically provided at high purity for research use.
- Antioxidative activity
- Inhibits lipid peroxidation
- Suppresses JNK and p38 MAPK phosphorylation
- Reduces caspase-3 activation
- Reported oral bioactivity
- High purity (99.78%)
- Available as solid and DMSO solution, including 10 mg solid
Medchemexpress LLC D-Glucuronic acid sodium salt monohydrate | 207300-70-7 | 5 G
D-Glucuronic acid sodium salt monohydrate is a primary constituent of various anti-inflammatory proteoglycans. It has the ability to promote embryonic development and inhibit cell aggregation. Upon metabolization into ethyl glucuronide, it activates Toll-like receptor 4 (TLR4), which can lead to pain. Both D-Glucuronic acid sodium salt monohydrate and its derivative, glucurono-lactone, can serve as liver detoxifiers for human health prevention, and its derivatives also demonstrate anti-tumor activity. The product has a purity of 98.0% and is intended for research use only.
- Promotes embryonic development and inhibits cell aggregation
- Activates Toll-like receptor 4 (TLR4)
- Functions as a liver detoxifier
- Demonstrates anti-tumor activity (derivatives)
- Intended for research use only
- High purity
Medchemexpress LLC Insulin Receptor Beta Antibody (YA341) | Protein A affinity purified | Predicted band size: 156 kDa; Observed band size: 95 kDa | 10 UL
Insulin Receptor Beta Antibody (YA341) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Insulin Receptor Beta. This antibody is developed for research use only and mediates the pleiotropic actions of insulin, playing a key role in cell growth, survival, and differentiation.
- Host: rabbit
- Clonality: recombinant, monoclonal
- Species reactivity: human, rat
- Immunogen: synthetic peptide corresponding to human insulin receptor (AA range: 930-970)
- Applications: WB (1:500-1:2000), ICC/IF (1:100-1:500)
- Purity: protein A affinity purified
- Conjugation: non-conjugated
- Formulation: supplied in 1*TBS (pH7.4), 0.05% BSA, 40% glycerol, and 0.05% sodium azide
- Storage: stored at -20°C for 1 year; avoid repeated freeze/thaw cycles
- Shipping: shipped with blue ice
Alkali Scientific Leupeptin Hemisulfate, 1 Milligram
Leupeptin Hemisulfate is a potent protease inhibitor available in a 1-milligram quantity. It is primarily used in biochemical research to inhibit serine, cysteine, and threonine proteases. Leupeptin is commonly employed to prevent proteolysis in experiments involving protein isolation, enzyme assays, and cell culture studies. By inhibiting a wide range of proteases, Leupeptin preserves the integrity of proteins during their extraction and purification processes. This reagent is essential for studies focusing on enzyme activity, protein-protein interactions, and various cellular mechanisms in both in vitro and in vivo research applications.
Apexbio Technology LLC PKH26 Red Fluorescent Cell Linker Kit(Synonyms: PKH26 Cell Membrane Dye, PKH26 Fluorescent Cell Labeling Kit), 250T.
PKH26 Red Fluorescent Cell Linker Kit comprises the red fluorescent probe PKH26 designed specifically to label cellular membranes PKH26 integrates stably into lipid regions of cell membranes emitting red fluorescence and enabling clear visualization of cells Due to low cytotoxicity low nonspecific background fluorescence and minimal dye transfer to neighboring unlabeled cells PKH26 has broad utility in tracking cells both in vitro and in vivo Its fluorescence is evenly partitioned between daughter cells during proliferation diminishing with each round of cell division facilitating proliferation assays PKH26 is frequently employed alone or in combination with PKH67 for cell tracking studies and proliferation analyses
Medchemexpress LLC Heparin Lithium salt | 9045-22-1 | 500 MG
Heparin Lithium salt is an anticoagulant that binds reversibly to antithrombin III (ATIII) and significantly inhibits exosome-cell interactions.
- Anticoagulant
- Binds reversibly to antithrombin III (ATIII)
- Significantly inhibits exosome-cell interactions