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Filtered Search Results
Apexbio Technology LLC Betamethasone Valerate 2152-44-5 500mg
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Betamethasone valerate (CAS 2152-44-5) is a small-molecule agonist targeting the glucocorticoid receptor It is designed to modulate inflammatory responses by altering gene transcription thereby regulating immune-mediated processes Betamethasone valerate exerts its biological activity primarily through glucocorticoid receptor agonism In in vitro studies betamethasone valerate inhibits radiolabeled glucocorticoid (dexamethasone) binding to human epidermis and mouse skin with IC50 values of 5 and 6 nM respectively Based on these pharmacological properties betamethasone valerate holds research potential in dermatological applications including investigations of recurrent aphthous stomatitis and inflammatory skin disorders
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Medchemexpress LLC Ethyl palmitate | 628-97-7 | 100 G
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Ethyl palmitate (Ethyl hexadecanoate) is an inhibitor of the CHIKV virus with an EC50 value of 0.0068 μM. It demonstrates anti-inflammatory activity by reducing levels of TNF-α, IL-6, and NF-κB in endotoxemic rats.
- Inhibits CHIKV virus E2 protein expression and viral activity with an EC50 of 0.0068 μM.
- Reduces plasma levels of TNF-α and IL-6, and decreases NF-κB expression in liver and lung tissues in endotoxemia rat models.
- Available with a purity of 99.09%.
- Available as a solid or liquid depending on temperature (<24°C solid, >26°C liquid).
- Soluble in DMSO (100 mg/mL).
- Molecular weight of 284.48, formula C18H36O2.
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Apexbio Technology LLC Clevidipine Butyrate 167221-71-8 10mg
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Clevidipine butyrate (CAS 167221-71-8) is a rapidly acting dihydropyridine calcium channel antagonist that selectively inhibits L-type calcium channels in vascular smooth muscle This inhibition leads to arterial vasodilation and subsequent reduction in blood pressure In vitro studies demonstrate an IC50 of 7 1 nM at a holding potential of -40 mV indicating high potency for its target Clevidipine butyrate is primarily investigated in the context of perioperative hypertension offering a research tool for evaluating acute blood pressure management and the pharmacodynamics of short-acting calcium channel blockade in vascular systems
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ABclonal Technology MonoMethyl-Histone H3-K27 Rabbit pAb
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
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Selleck Chemical LLC Ethyl acetoacetate
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Ethyl acetoacetate found in coffee and coffee products as well as in strawberry and yellow passion fruit juice is a flavouring agent used as a chemical intermediate in the production of a wide variety of compounds
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Selleck Chemical LLC Paliperidone Palmitate
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Paliperidone Palmitate (9-hydroxyrisperidone palmitate) is a palmitate ester of paliperidone which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class
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Selleck Chemical LLC 4-Octyl Itaconate
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4-Octyl Itaconate activates Nrf2 signaling to inhibit the production of pro-inflammatory cytokines in human macrophages and systemic lupus erythematosus (SLE) patient-derived PBMCs
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Selleck Chemical LLC 4-Octyl Itaconate
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4-Octyl Itaconate activates Nrf2 signaling to inhibit the production of pro-inflammatory cytokines in human macrophages and systemic lupus erythematosus (SLE) patient-derived PBMCs
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Selleck Chemical LLC 4-Octyl Itaconate
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4-Octyl Itaconate activates Nrf2 signaling to inhibit the production of pro-inflammatory cytokines in human macrophages and systemic lupus erythematosus (SLE) patient-derived PBMCs
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Selleck Chemical LLC Dibutyl sebacate
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Dibutyl sebacate is an organic chemical which is mainly used as a plasticizer in the production of plastics
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Medchemexpress LLC Sodium butyrate | 156-54-7 | 99.8% | 5 G
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Sodium butyrate | 156-54-7 | 99.8% | 5 G
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Medchemexpress LLC Monomethyl auristati | 100MG
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Monomethyl auristati | 100MG
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Sigma Aldrich Fine Chemicals Biosciences Methyl Myristate | 124-10-7 | MFCD00008983 | 25g
Methyl Myristate | Purity: 99% | Mol Wt: 242.4 | 124-10-7 | MFCD00008983 | 25g
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Chemscene ChemScene | tert-Butyl 7-bromoheptanoate | 1G | CS-0136661 | 0.97 | 51100-47-1| MFCD27924668 | 265.19
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ChemScene | tert-Butyl 7-bromoheptanoate | 1G | CS-0136661 | 0.97 | 51100-47-1| MFCD27924668 | 265.19
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Selleck Chemical LLC Doxylamine Succinate S4240-50mg
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Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects
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