Glycerolipids
Medchemexpress LLC 1H-Indole-2-carbonitrile, 6-hydroxy-1-(1H-pyrazol-4-ylmethyl)-5-[[4-[[6-(2,2,2-trifluor... | 1857417-10-7 | 98.2% | 566.60 | 1 MG
MI-538 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM. It is for research use only and not sold to patients.
- Inhibits the proliferation of MLL leukemia cells with a GI50 of 83 nM.
- Shows selectivity towards MLL fusion protein transformed cells.
- Binds to menin with a Kd of 6.5 nM.
- Leads to strong down-regulation of Hoxa9 and Meis1 gene expression.
- Reduces tumor volume in mice xenografts.
- Improved exposure and Cmax in blood plasma.
- Low clearance and a half-life of about 1.6 hours.
- High oral bioavailability (~50%).
- Soluble in DMSO.
- Soluble in various in vivo protocols, including 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline.
Cambridge Isotope Laboratories TRIPALMITIN (TRISPALMITOYL-D93, 98%), 0.5 G
TRIPALMITIN (TRISPALMITOYL-D93, 98%), 0.5 G
Selleck Chemical LLC Triolein S3590-25mg
Triolein is an inhibitor of metalloproteinase-1 (MMP-1) and reduces both the expression of IL-6 and ROS generation in irradiated keratinocytes
Aobchem 1-(Allyloxy)-2-bromo-4-chlorobenzene | ≥95% | CAS 68223-98-3 | C9H8BrClO | 10g
1-(Allyloxy)-2-bromo-4-chlorobenzene | ≥95% | CAS 68223-98-3 | C9H8BrClO | 10g
Aobchem 1-(Allyloxy)-3-bromobenzene | ≥97% | CAS 41388-50-5 | C9H9BrO | 10g
1-(Allyloxy)-3-bromobenzene | ≥97% | CAS 41388-50-5 | C9H9BrO | 10g
Aobchem 2-(Allyloxy)-1 4-dimethylbenzene | ≥95% | CAS 3727-20-6 | C11H14O | 5g
2-(Allyloxy)-1 4-dimethylbenzene | ≥95% | CAS 3727-20-6 | C11H14O | 5g
Sigma Aldrich Fine Chemicals Biosciences Glyceryl tributyrate >=99% | 60-01-5 | MFCD00009392 | 25ML
Glyceryl tributyrate >=99% | Purity: >=99% | Mol Wt: 302.36 | 60-01-5 | MFCD00009392 | 25ML
Medchemexpress LLC Triolein (standard) | 122-32-7 | 885.43 | 25 MG
Triolein (Standard) is the analytical standard of Triolein intended for research and analytical applications. It is a symmetric triacylglycerol that reduces upregulation of MMP-1 and has strong antioxidant and anti-inflammatory activities. This compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS, serving as a reference standard supplied for assay.
- Analytical standard for research
- Symmetric triacylglycerol
- Reduces upregulation of MMP-1
- Strong antioxidant and anti-inflammatory activities
- Suitable for HPLC research experiments
- Suitable for GC research experiments
- Suitable for MS research experiments
Medchemexpress LLC Triacetin (standard) | 102-76-1 | 99.9% | 100 MG
Triacetin (Standard) is the analytical standard of Triacetin, a synthetic compound that is a triester of glycerol and acetic acid. It is intended for research and analytical applications.
- Analytical standard for research and analysis
- Used in qualitative, quantitative, and methodological research experiments (e.g., HPLC, GC, MS)
- For research use only
Medchemexpress LLC Triacetin | 102-76-1 | MFCD00008716 | >99.9% | 1 G
Triacetin (Glyceryl triacetate) is a synthetic, orally active compound that acts as a triester of glycerol and acetic acid. It readily crosses the blood-brain barrier and plasma membrane, increasing acetate bioavailability in glioma cells. This leads to glioma cell growth arrest and apoptosis.
- Induces glioma cell growth arrest
- Promotes apoptosis in glioma cells
- Increases histone acetylation
- Enhances chemotherapeutic efficacy of Temozolomide