Steroids and derivatives
Sigma Aldrich Fine Chemicals Biosciences Kaempferol 97.0 HPLC100MG
KAEMPFEROL0 Kaempferol 97.0 HPLC100MG
Sigma Aldrich Fine Chemicals Biosciences Cholecalciferol (Activated 7-Dehydrocholesterol, Calciol) | CAS 67-97-0 | MDL
Cholecalciferol (Activated 7-dehydrocholesterol, Calciol) | Purity: 98% | M. W.: 384.64 | 67-97-0 |
Sigma Aldrich Fine Chemicals Biosciences Ouabain octahydrate >=95% (HPLC), powder | 11018-89-6 | MFCD00149240 | 25G
Ouabain octahydrate >=95% (HPLC), powder | Purity: >=95% (HPLC) | Mol Wt: 728.77 | 11018-89-6 | MFCD00149240 | 25G
Sigma Aldrich Fine Chemicals Biosciences Ouabain octahydrate >=95% (HPLC), powder | 11018-89-6 | MFCD00149240 | 5G
Ouabain octahydrate >=95% (HPLC), powder | Purity: >=95% (HPLC) | Mol Wt: 728.77 | 11018-89-6 | MFCD00149240 | 5G
Medchemexpress LLC Estra-1,3,5(10)-trien-17-one, 3-[(aminosulfonyl)oxy]- | 148672-09-7 | 99.99% | C18H23NO4S | 50 MG
Estrone O-sulfamate is a potent steroid sulfatase (STS) inhibitor. It exhibits inhibitory activity for STS in placental microsomes preparation and in MCF-7 cells, and can be utilized for cancer research.
- Potent steroid sulfatase (STS) inhibitor
- Exhibits inhibitory activity for STS in placental microsomes and MCF-7 cells
- Can be used for cancer research
- Shows inhibitory activity against human steroid sulfatase over-expressed in CHO cells
- Exhibits antiproliferative activity against various human cancer cell lines
- Inhibits human placental steroid sulfatase in HEK293 cells
- Inhibits estrone sulfatase in JEG-3 cells
- Causes growth inhibition and antiproliferative activity in MCF7 cells
Sigma Aldrich Fine Chemicals Biosciences Estriol 16alpha beta D glu10MG
Estriol 16alpha beta D glu10MG
Sigma Aldrich Fine Chemicals Biosciences Methyl-d3-amine hydrochlor1G
methyl Methyl-d3-amine hydrochlor1G
Sigma Aldrich Fine Chemicals Biosciences Norethindrone acetate United States Pharmacopeia (USP) Reference Standard | 51-98-9 | MFCD00271615 | 100MG
Norethindrone acetate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 340.46 | 51-98-9 | MFCD00271615 | 100MG
Sigma Aldrich Fine Chemicals Biosciences Cortisone 2246691212 d8 981MG
Cortisone 2246691212 d8 981MG
Medchemexpress LLC Fluorometholone acetate | 3801-06-7 | 98.5% | 25 MG
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It potently inhibits carbonic anhydrase (CA) and has anti-inflammatory effects, making it suitable for external ocular inflammation research.
- Potently inhibits carbonic anhydrase (CA)
- Inhibits hCA-I with IC50 of 2.18 μM
- Inhibits hCA-II with IC50 of 17.5 μM
- Used in inflammation/immunology research
- Appears as a white to off-white solid
Apexbio Technology LLC Ethinyl Estradiol 57-63-6 10mM (in 1mL DMSO)
Ethinyl Estradiol (57-63-6) is a small-molecule estrogen receptor agonist targeting intracellular estrogen receptors It is designed to activate these receptors thereby regulating transcription of estrogen-responsive genes and influencing reproductive biology and cell proliferation pathways Ethinyl Estradiol exerts its biological activity primarily through direct binding to estrogen receptors leading to the modulation of endocrine-regulated mechanisms Based on these pharmacological properties Ethinyl Estradiol holds research potential in studies of receptor-mediated responses endocrine regulation mechanisms synthetic hormone interactions drug interactions contraceptive mechanisms and hormone-dependent physiological processes
Apexbio Technology LLC Dexamethasone acetate 1177-87-3 5g
Dexamethasone acetate a synthetic glucocorticoid acts by binding to glucocorticoid receptors influencing gene transcription to suppress inflammatory and immune responses By modulating cytokine production and inhibiting interleukin (IL) signaling pathways dexamethasone acetate serves as an interleukin receptor modulator Typically applied in research related to inflammation autoimmune diseases and cytokine-mediated cellular events it is extensively utilized in functional assays to understand receptor-ligand interactions signal transduction and therapeutic mechanisms Studies report variable IC50 values depending on cell type and assay conditions with typical IC50 ranges documented from 1-10 nM in receptor binding assays providing a reference concentration range for experimental designs