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Two-carbon nitrogen ring bases (adenine and guanine) covalently linked to a sugar (ribose or deoxyribose) and one to three phosphate groups; can function as extracellular messengers, antimetabolites, and chain terminators that inhibit viral DNA polymerase.
2-Amino-ATP is a modified nucleotide structurally related to ATP (adenosine triphosphate) featuring an amino substitution at the adenine ring s 2-position It acts as an ATP analog capable of competitively binding at the active sites of ATP-dependent enzymes potentially modulating their enzymatic activity and influencing downstream signaling pathways In research settings 2-Amino-ATP serves as a molecular tool to examine substrate specificity mechanistic aspects of ATP-binding enzymes (e g kinases and ATPases) and nucleotide-dependent receptor interactions facilitating studies of nucleotide signaling and cellular metabolism
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Adenosine N1-oxide is an adenosine derivative used in research with reported oral anti-inflammatory activity. Isolated from royal jelly, it has been reported to promote osteogenic and adipocyte differentiation and is supplied as a purified solid for laboratory studies.
Oral active anti-inflammatory agent.
Promotes osteogenic and adipocyte differentiation.
Molecular formula C10H13N5O5; molecular weight 283.24 g/mol.
Purity 99.5%.
Available in small milligram pack sizes for research use, e.g., 10 MG.
For research use only.
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ATP-Red 1 is a multisite-binding switchable fluorescent probe that selectively and rapidly responds to intracellular concentrations of ATP in living cells.
Multisite-binding switchable fluorescent probe
Selectively and rapidly responds to intracellular concentrations of ATP in living cells
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Adenosine 5'-diphosphoribose is an endogenous nucleotide (ADP ribose) consisting of an adenine base linked to a ribose and two phosphate groups. Supplied as a research-grade solid, it is used in biochemical and cellular assays to investigate ADP-ribosylation signaling, DNA damage response pathways, and calcium-permeable TRPM2 channel activation. The material is provided in assay-friendly quantities with supporting documentation for safe handling.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo, providing metabolic energy to drive metabolic pumps and serving as a coenzyme in cells. It is also an important endogenous signaling molecule in immunity and inflammation.
Synergistically activates the NLRP3 inflammasome in HGFs when co-treated with LPS.
Induces secretion of IL-1β, KC, and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.
Promotes neutrophil chemotaxis in vitro.
Protects mice against bacterial infection in vivo.
Induces the secretion of IL-1β, KC, and MIP-2 and neutrophils recruitment in vivo.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ADP-β-S trilithium is the trilithium salt of adenosine 5'-β-thiodiphosphate, used in research as a P2Y12 receptor activator. It is supplied as a white to off-white solid (CAS 73536-95-5) with listed purity ~94.9% and molecular formula C10H12Li3N5O9P2S. Store sealed and away from moisture; in solution store at -80°C for long-term stability.
Activator of P2Y12 receptor in cellular assays.
Upregulates IL-1β and IL-6 production in microglial models.
Promotes NF-κB phosphorylation and nuclear translocation.
Enhances NLRP3 inflammasome activation in relevant studies.
Provided as a solid suitable for preparation of assay solutions.
Stable under recommended sealed, low-temperature storage conditions.
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