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Two-carbon nitrogen ring bases (adenine and guanine) covalently linked to a sugar (ribose or deoxyribose) and one to three phosphate groups; can function as extracellular messengers, antimetabolites, and chain terminators that inhibit viral DNA polymerase.
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GTP-14564 is a tyrosine kinase inhibitor that targets internal tandem duplication (ITD) and FLT3. It inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
Tyrosine kinase inhibitor
Targets ITD and FLT3
Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells
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Adenosine 5-triphosphate (ATP CAS 34369-07-8) also known as ATP disodium salt hydrate is a nucleotide central to cellular energy transfer It functions as the primary intracellular energy carrier undergoing hydrolysis to release energy required for numerous biochemical processes including muscle contraction signal transduction and biosynthetic reactions ATP also serves as a substrate for kinases in phosphorylation events and plays a regulatory role in purinergic signaling pathways In biomedical research ATP is widely used to study cellular metabolism enzyme activities and receptor-mediated responses
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Guanosine 5'-triphosphate trisodium salt hydrate is an activator of the signal transducing G proteins and serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
Activator of signal transducing G proteins
Energy-rich precursor in DNA and RNA biosynthesis
For research use only
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Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates the adenosine 5'-triphosphate-sensitive K+ channel. It acts as an iron mobilizer by forming a complex with hepcidin, inhibiting the hepcidin-ferroportin (FPN) interaction, and modulating the IL-6/stat-3 pathway. It has been shown to ameliorate Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO4 and can be used in AI research.
2p-O-Methyl-2-Amino-ATP is a modified nucleoside triphosphate incorporating methylation at the ribose 2 -hydroxyl group and an amino substitution at the 2 position of the adenine base It is designed to alter nucleotide biochemical properties impacting RNA stability and structure upon enzymatic incorporation In in vitro transcription assays 2p-O-Methyl-2-Amino-ATP demonstrates an ability to increase RNA resistance to exonuclease-mediated degradation and induce altered RNA secondary structures Based on these properties 2p-O-Methyl-2-Amino-ATP holds research potential in studies of RNA folding dynamics stability assays RNA-protein interactions and analyses involving chemically modified RNA in biomedical research
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Adenosine receptor inhibitor 1 is a potent and selective adenosine receptor (AR) inhibitor. It demonstrates antinociceptive, anti-inflammatory, and peripheral analgesic effects, with potential applications in cancer and neurodegenerative disease research.
Potent and selective adenosine receptor (AR) inhibitor.
Exhibits antinociceptive activity.
Shows anti-inflammatory effect.
Possesses peripheral analgesic effect.
Suitable for research into cancer and neurodegenerative diseases.
Provided as a white to off-white solid.
Purity of 98.3%.
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Adenosine 5'-diphosphoribose is a nucleoside diphosphate reagent used in biochemical research. It functions as a metabolite and signaling molecule in nucleotide metabolism and is supplied as a solid for laboratory assays and enzymology.
Applicable to studies of nucleotide signaling and enzymatic activity.
Suitable for use in biochemical assays and cellular experiments.
Supplied in small research quantities (e.g., 10 mg) for assay development.
Identified by CAS, molecular formula, and molecular weight for accurate reference.
Intended for research use only; not for diagnostic or clinical use.
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Adenosine dialdehyde is a purine nucleoside analogue that acts as a potent inhibitor of S-adenosylhomocysteine hydrolase (SAHH). It is used as a biochemical research reagent to investigate methylation pathways and methyltransferase activity, and is supplied in solid milligram quantities and as a 10 mM solution in DMSO for convenient assay preparation.
Potent SAHH inhibitor for methylation pathway studies.
Supplied in both solid and ready-to-use solution formats.
High stated purity for analytical and research applications.
Compatible with enzyme inhibition assays and cellular studies.
Provided with datasheet, certificate of analysis, and safety data sheet for compliance.
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2 -O-Methyl-ATP is a chemically modified derivative of ATP in which the hydroxyl group at the ribose 2 position is replaced with a methyl group This ribose modification confers resistance to nuclease-mediated degradation thereby increasing its biological stability The modified nucleotide is commonly employed in biomedical research to investigate RNA structure-function relationships and RNA modification pathways and to study interactions influencing RNA polymerase specificity and catalytic activity Additionally 2 -O-Methyl-ATP serves as a tool in probe design for RNA interference experiments and aids in elucidating intracellular metabolic pathways involving nucleotide analogs
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Acyclovir triphosphate sodium (AcycloGTP sodium) is a derivative of Acyclovir that functions as an inhibitor of viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). This compound is also recognized as an inhibitor of HIV-1 reverse transcriptase, ultimately leading to the termination of viral DNA synthesis. It is intended for research use only.
Competitively inhibits viral DNA polymerase.
Acts as an analog to deoxyguanosine triphosphate (dGTP).
Inhibits HIV-1 reverse transcriptase.
Causes termination of viral DNA synthesis.
Available for research purposes.
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Guanosine 5'-triphosphate (trisodium salt) is a G protein signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. It can promote myogenic cell differentiation and induce human myogenic precursor cells to release exosomes. This product is for research use only and holds promise for research in biosynthesis and skeletal muscle regeneration.
Acts as a G protein signaling activator
Functions as a high-energy precursor in the biosynthesis of DNA and RNA nucleotide units
Promotes myogenic cell differentiation by upregulating miRNA and myogenic regulatory factor expression
Induces human myogenic precursor cells to release exosomes containing guanosine molecules
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