NAD-dependent Glucose dehydrogenase (GDH-NAD) (EC 1.1.1.47) is an NAD-dependent oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP+ to NADPH or, to a lesser extent, NAD+ to NADH. This enzyme is versatile, accepting both NAD+ and NADP+ as cofactors, making it suitable for the regeneration of NADH and NADPH. It appears as a solid with a color ranging from white to off-white and is intended for research use only.
- Catalyzes oxidation of β-D-glucose to β-D-glucono-1,5-lactone
- Reduces NADP+ to NADPH or NAD+ to NADH
- Accepts both NAD+ and NADP+ as cofactors
- Suitable for regeneration of NADH and NADPH
- Appears as a solid with a color ranging from white to off-white
- Intended for research use only