Pyridine nucleotides
Sigma Aldrich Fine Chemicals Biosciences beta Nicotinamide adenine5G
adenine beta Nicotinamide adenine5G
Sigma Aldrich Fine Chemicals Biosciences beta Nicotinamide adenine100MG
beta Nicotinamide adenine100MG
Sigma Aldrich Fine Chemicals Biosciences beta Nicotinamide adenine500MG
beta Nicotinamide adenine500MG
Sigma Aldrich Fine Chemicals Biosciences Nicotinamide 1N6 ethenoade25MG
Nicotinamide 1N6 ethenoade25MG
Selleck Chemical LLC Nicotinamide S1899-1g
Nicotinamide a water-soluble vitamin is an active component of coenzymes NAD and NADP and also act as an inhibitor of sirtuins
Medchemexpress LLC α-NAD (α-Nicotinamide Adenine Dinucleotide) | 7298-93-3 | 98.0% | 5 MG
α-NAD (α-Nicotinamide Adenine Dinucleotide) serves as a substrate for renalase and functions as an analog of β-NAD, influencing the kinetics of NAD-dependent enzymes, while also playing a crucial role as a cofactor in mitochondrial oxidation-reduction reactions.
- Functions as a substrate for renalase.
- Acts as an analog of β-NAD.
- Impacts the kinetics of NAD-dependent enzymes.
- Plays a vital role as a cofactor in mitochondrial oxidation-reduction reactions.
Medchemexpress LLC Oxidized low density lipoprotein (mouse) | ≥98% | 1 MG
Oxidized low density lipoprotein (mouse) (Mouse ox-LDL) is an oxidized low density lipoprotein (LDL). It induces atherosclerosis (AS) by facilitating endothelial dysfunction and accelerating the VSMCs growth and migration, making it suitable for constructing an in vitro model of AS.
- Induces atherosclerosis (AS)
- Facilitates endothelial dysfunction
- Accelerates VSMCs growth and migration
- Can be used to construct an in vitro model of AS
- Upregulates mRNA and protein expressions of long noncoding RNA TUG1 and receptor tyrosine kinase-like orphan receptor 2 (ROR2)
- Promotes the proliferation of HA-VSMCs
- Enhances migration and invasion abilities
- Increases the expressions of metastasis-related proteins β-catenin and Vimentin in human aortic vascular smooth muscle cells
Medchemexpress LLC Nicotinamide | 98-92-0 | 99.9% | 1 G
Nicotinamide, also known as Niacinamide, is a form of vitamin B3. It functions as an inhibitor of SIRT1 and SIRT2, increasing cellular NAD+, ATP, and ROS levels. It is involved in various biological processes, including tumor growth inhibition and anti-HBV activity.
- SIRT2 inhibitor (IC50: 2 μM)
- SIRT1 inhibitor (IC50: 50-180 μM)
- Increases cellular NAD+, ATP, and ROS levels
- Inhibits tumor growth
- Possesses anti-HBV activity
- Promotes pancreatic cell differentiation
- Reduces cell number in melanoma cells
Medchemexpress LLC NAD+ (beta-Nicotinamide Adenine Dinucleotide) | 53-84-9 | 99.96% | 1 ML
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. Found widely in nature, it is involved in numerous enzymatic reactions, serving as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide).
- Involved in numerous enzymatic reactions as an electron carrier
- White to off-white solid appearance
- Available in solid and solution forms
Sigma Aldrich Fine Chemicals Biosciences beta Nicotinamide adenine
-Nicotinamide adenine dinucleotide (-NAD) is a ubiquitous biomolecule containing an adenylic acid and a nicotinamide-5AE-ribonucleotide group linked together by a pyrophosphate moiety. In NAD complexes the enzyme-cofactor interactions are highly conserved.